Parkinson Disease (PD) is a degenerative disease of the extrapyramidal motor system. The formations midbrain are affected and expressed in 1. Tremor, 2. Hypokinesia, 3. Muscle rigidity, 4. Postural instability. Alzheimer's (AD) progressive form senile dementia, leading to complete loss cognitive abilities, developing mainly after 60-65 years age. With these diseases, large number brain structur...

BACKGROUND Parkinson's disease is caused by a dopamine deficiency state in the fore brain area. Dopamine receptor agonists, MAO-B inhibitors, and N-Methyl-D-Aspartate (NMDA) receptor antagonists are known to have antiparkinson effect. Levodopa, a dopamine structural analog, is the best currently available medication for the treatment of Parkinsons disease. Unfortunately, it also induces side ef...

No wonder you activities are, reading will be always needed. It is not only to fulfil the duties that you need to finish in deadline time. Reading will encourage your mind and thoughts. Of course, reading will greatly develop your experiences about everything. Reading parkinsons disease ii aging and neuroendocrine relationships is also a way as one of the collective books that gives many advant...

We present a new Dutch dysarthric speech database containing utterances of neurological patients with Parkinsons disease, traumatic brain injury and cerebrovascular accident. The speech content is phonetically and linguistically diversified by using numerous structured sentence and word lists. Containing more than 6 hours of mildly to moderately dysarthric speech, this database can be used for ...

he development of therapeutic interventions for genetic disorders and diseases that affect the central nervous system (CNS) has proven challenging. There has been significant progress in the development of gene therapy strategies in murine models of human disease, but gene therapy outcomes in these models do not always translate to the human setting. Therefore, large animal models are crucial t...