Afsaneh Koochek ([email protected]) Parvin Mirmiran ([email protected]) Kristina Sundquist ([email protected]) Firoozeh Hosseini ([email protected]) Tohid Azizi ([email protected]) Ali S Moeini ([email protected]) Sven-Erik Johansson ([email protected]) Brita Karlström ([email protected]) Fereidoun Azizi ([email protected]) Jan Sundquist (Jan.Sundqu...

The focal adhesion (FA) protein α-Parvin (αPv) has been shown to regulate integrin signalingand integrin-actin linkage. Here we report that the conditional deletion of the αPv gene inkeratinocytes leads to impaired hair follicle (HF) morphogenesis, epidermal hyperplasia andmicro-blistering. Expression of integrin α6 was reduced on αPv-deficient keratinocytes,leading to defects i...

E ndothelial cells (ECs) covering the inner surface of blood and lymphatic vessels 1 create an interface between circulating blood and lymph and the surrounding tissue. Hence, ECs are crucially involved in maintaining the integrity of all tissues. In addition, the formation of new vessel, eg, during wound healing processes, is determined by ECs. 2 Thus, the maintenance of a structural and funct...

Samples with Increased Urea, J. Keith Pinckard, Janet Zahn, Lori Ashby, Curtis A. Parvin, and Mitchell G. Scott ( Washington University School of Medicine, Division of Laboratory Medicine, Box 8118, 660 South Euclid Ave., St. Louis, MO 63110; 2 Barnes-Jewish Hospital, Department of Laboratories, One Barnes-Jewish Hospital Plaza, St. Louis, MO 63110; * author for correspondence: fax 314362-1461,...

Sevil Hakimi, Sakineh Hajebrahimi, Parvin Bastani, Elham Aminian, Samieh Ghana, Marzieh Mohammadi. Msm, PhD. Assistant Professor, Tabriz University of Medical Science, Tabriz, Iran; MD. Professor, Tabriz University of Medical Science, Tabriz, Iran; Women’s Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; MSm Student. Tabriz University of Medical Science,...

Raheleh Janani, Abdollah Jannatdoost, Alehe Seyedrasuli, Leila Valizadeh, Parvin Sarbakhsh. Member of educational board of nursing and midwifery faculty of Tabriz University of medical sciences, Iran; Department of medical surgical, nursing and midwifery faculty, Tabriz University of medical sciences, Iran; MD neonatal nursing of Alzahra hospital and head of research of Alzahra research committ...

Introduction Extracellular signaling is commonly mediated through mechanisms that rely on protein-protein interactions and protein phosphorylation. The dynamics of protein-protein interactions are often dependent on the activation of a particular signal transduction pathway. Even a single protein can affect various cellular functions by interacting with different partners in response to extrace...

The heterotrimeric protein complex containing the integrin linked kinase (ILK), parvin, and PINCH proteins, termed the IPP complex, is an essential component of focal adhesions, where it interacts with many proteins to mediate signaling from integrin adhesion receptors. Here we conduct a biochemical and structural analysis of the minimal IPP complex, comprising full-length human ILK, the LIM1 d...