Haemovigilance is a system with standard program to cover the entire transfusion chain, monitor, evaluate and analyse the data to improve patients’ safety. We report the implemented haemovigilance system in hospitals and transfusion reactions (TR) in Iran. Methods and Materials: This was a prospective descriptive study. The national reporting system for transfusion incidents was introduced in ...

Pharmaceutical companies must find a better way to increase their output of truly new drugs for the benefit of patients and for their business survival. Here, I highlight a general perspective from within pharmaceutical research as it pertains to research advances in chemistry, biology, pharmacology, pharmacokinetics and toxicology that, if well integrated, stands to put the industry on a produ...

This chapter explores the ethical responsibility of health care providers to administer safe clinical care. It further explores the challenges that such providers can experience in recognizing, reporting, and disclosing medical errors. Medical errors can cause serious harm (to the patient, provider and institution or clinic) and can prove to be expensive, stressful, time-consuming, and personal...

Six months administration of bromocriptine mesylate significantly decreased glycated hemoglobin (HbA1c), fasting blood sugar, postprandial blood sugar, and weight of 22 Indian obese patients with type 2 diabetes mellitus with no serious adverse events. Therefore, the novel mechanism of action, efficacy and acceptable safety profile makes this drug an attractive option for treatment of obese typ...

Critics of the drug safety system have discussed many different potential reforms, ranging from mandatory registration of clinical trials to increasing the power of regulatory agencies, but few have discussed one of the most important ways of enhancing safety: increasing the number of long-term studies of medications. Long-term studies of the risks and benefits of drugs can provide useful infor...

objective: non:union: is defined as a minimum of a 9-month period of time since an injury with no visibly progressive signs of healing for 3 months. recent studies show that application of mesenchymal stromal cells (mscs) in the laboratory setting is effective for bone regeneration. animal studies have shown that mscs can be used to treat non:union:s. for the first time in an iranian population...