The paired-domain-containing Pax transcription factors play an important role in the development of a range of organ, tissue and cell types. Although DNA binding elements and target genes for Pax proteins have been identified, how these proteins identify appropriate DNA elements and regulate different genes in different cellular contexts is not well understood. To investigate the relationship b...

PURPOSE The corneal endothelium is a monolayer of cells in the posterior cornea that is responsible for maintaining a clear cornea. Corneal endothelial cells may be induced to divide, but it has been held that they do not divide in the normal cornea of an adult human. Some studies have suggested that a stem cell population for the corneal endothelium exists. This population could give rise to m...

The paired box-containing (pax) gene family encodes a group of putative transcription factors differentially expressed during embryonic development. In this study, we describe the cloning and expression of a zebrafish gene pax[zf-b], which most probably is a direct homologue to the mouse Pax2 gene. The putative protein encoded by pax[zf-b] contains a paired box, an octapeptide, but no homeobox....

Several types of thyroid cancer ± classic papillary, anaplastic and medullary thyroid carcinoma ± can be confidently diagnosed and distinguished through fineneedle aspiration cytology (FNAC) of a thyroid nodule, thanks to their characteristic morphology and additional immunocytochemistry. In contrast, the finding of follicular thyroid neoplasia, a cytological group diagnosis encompassing the th...

Several stages in the lens determination process have been defined, though it is not known which gene products control these events. At mid-gastrula stages in Xenopus, ectoderm is transiently competent to respond to lens-inducing signals. Between late gastrula and neural tube stages, the presumptive lens ectoderm acquires a lens-forming bias, becomes specified to form lens and begins differenti...

The aim of this paper is to design an approach evaluate the expected efficiency and performance future airport infrastructure. First, sampling method select similar airports developed based on socioeconomic operational variables that are summarized in a proxy variable; second, ARIMA-GARCH-Bootstrap applied forecast selected outputs (PAX ATMS) whilst inputs (Cities, Gates, Runaways, Airport Size...