Abortions caused by Neospora caninum are a serious problem in cattle production and require effective immunoprophylaxis. The objective of this work was to assess the humoral immune response four recombinant (r) N. antigens after immunisation challenge. MIC1 MIC3 proteins from micronemes, SRS2 surface tachyzoites, GRA7 dense granules were expressed as truncated Escherichia coli. Cationic liposom...

This study assessed the effectiveness of a mutant strain of Toxoplasma gondii (RH strain) lacking the mic1 and mic3 genes (Mic1-3KO) against Toxoplasma abortion in sheep. Ewes were inoculated subcutaneously with 10(5) Mic1-3KO tachyzoïtes in three independent experiments. Following vaccination, Mic1-3KO induced a mild febrile response and serum IgG antibodies, which persisted throughout the exp...

Toxoplasma gondii is a successful opportunistic protozoan distributed worldwide, which can infect all vertebrates, leading to serious infection, blindness, and abortion. Micronemal (MIC) proteins are critically important for T. gondii infection, as they participate in various stages of the Toxoplasma life cycle, including invasion and attachment to host cells. MIC8 secretion relies on the conce...

Host cell attachment by Toxoplasma gondii is dependent on polarized secretion of apical adhesins released from the micronemes. Subsequent translocation of these adhesive complexes by an actin-myosin motor powers motility and host cell invasion. Invasion and motility are also accompanied by shedding of surface adhesins by intramembrane proteolysis. Several previous studies have implicated rhombo...

introduction: candida albicans (ca) is by far the most common yeast of oral infections, including endodontic infections. the aim of this study was to evaluate and compare the antifungal effect of white-colored mineral trioxide aggregate (wmta) and portland cement (pc) using a tube-dilution test. materials and methods: wmta and pc were tested freshly mixed and after 24 h. the experiment was perf...

the objective of this study was to investigate the effect of principal components (pc) of the regression coefficients (co)variance matrix on the lactation curve, and on the formation of selection index to modify the curve, based on these pc’s, and as well to estimate additive genetic and phenotypic variances and heritability of the constructed selection index. lactation period of 301 d (5-305) ...

background: prostate specific antigen (psa) has been used as a screening test for the early detection of prostate cancer (pc) for many years. although the introduction of psa test led to a considerable increase in reported prostate cancer cases, there is still some controversy over the sensitivity and specificity of this marker in distinguishing pc patients from those with benign prostate hyper...