Parkinson's disease (PD) is a complex multifactorial ailment predetermined by the interplay of various environmental and genetic factors. Systemic and intracellular magnesium (Mg) deficiency has long been suspected to contribute to the development and progress of PD and other neurodegenerative diseases. However, the molecular background is unknown. Interestingly, gene SLC41A1 located in the nov...

In this work, a self-powered photodetector device is fabricated through the integration of a palladium-doped molybdenum disulfide thin film on silicon (Pd-MoS2/Si). The substitution of host Mo atoms with Pd dopants in the MoS2 film is revealed by structural and chemical analysis techniques. Due to the incorporation of Pd atoms into the MoS2 films, the photovoltaic characteristics of the fabrica...

Pd-catalyzed asymmetric allylic substitution (AAS) is a highly effective method for producing chiral molecules with alkene-substituted frameworks which can be further derivatized. However, its stereochemical outcome affected by the steric requirements of substrate and only narrow set nucleophiles yield excellent enantioselectivities. In this regard, phosphite-oxazolines have emerged as strong c...

The kinetics of the transmetalation reaction between trans-[PdCl(C6Cl2F3)(PPh3)2] and [ZnMeCl(THF)2] shows a complex dependence on [PPh3] for rate formation different products: cis trans-[Pd(C6Cl2F3)Me(PPh3)2], trans-[PdClMe(PPh3)] (which further reacts with [ZnClMe(THF)2]), [Zn(C6Cl2F3)Cl(THF)2]. To better understand system reactions trans-[Pd(C6Cl2F3)Me(PPh3)2] [ZnCl2(THF)2] (the retro-transm...

The semi-hydrogenation reaction of alkynes is important in the fine chemicals and pharmaceutical industries, it thus to find catalytic processes that will drive efficiently at a low cost. real challenge alkyne-to-alkene while avoiding over-hydrogenation saturated alkane moiety. problem more difficult when dealing with aromatic substitution alkyne center. Simple photocatalysts based on Palladium...

Abstract High enantioselectivities (up to 99 %) and activities (TOF's up >4000 h −1 ) are accomplished in the Pd‐catalyzed allylic substitution of a wide range substrate types nucleophiles using family phosphite‐oxazoline ligands. These ligands were derived from PHOX ligand by exchanging phosphine moieties biaryl phosphites methylene spacer was introduced between oxazoline phenyl ring. The s...

Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzheimer's disease. Ten of fifteen causative genes linked to familial forms of PD have been reported to cause autosomal recessive forms. Among them, mutations in the PTEN-induced kinase 1 (PINK1) gene were shown to be responsible for a phenotype characterized by early onset, good response to levodopa, and a ben...