We have previously established that the relative concentrations of propylene glycol and ethanol as a binary solvent system have a significant effect on the skin penetration of 2% solutions of minoxidil at 50 microL/cm2. The present work extends these studies and investigates the penetration of minoxidil from the different vehicle combinations as functions of application volume and occlusion. De...

UNLABELLED The penetration of a sealant into the tooth fissures can establish longer retention time for a pit and fissure sealant restoration. AIM This in vitro study was to evaluate the penetration ability of two low-viscosity resin materials, a composite and a compomer, applied with and without their bonding agents in comparison to an unfilled resin sealant. METHODS Forty premolars with s...

achieving a desirable percutaneous absorption of drug molecule is a major concern in formulating dermatological products. the use of penetration enhancers could provide a successful mean for this purpose. the aim of this study was to evaluate the effect of incorporating a few common penetration enhancers (in different concentrations) into a 0.5% w/w piroxicam (model drug) gel formulation, on th...