This study evaluated the sedative, and anticonvulsant activities of aqueous (AESM) ethanol (EESM) dried leaf extracts Solenostemon monostachyus. The sedative effect was with ketamine-induced hypnosis (100 mg/kg, i.p.). Also, activity using pentylenetetrazole (PTZ)-induced convulsion (85 i.p.), strychnine-induced (2 i.p.) maximal electroshock (MES)-induced models. AESM (200 p.o.) gave 66.67% pro...

Considering the prevalence of epilepsy and problems associated with currently available antiepileptic drugs like side effects, resistance, safety issue high cost, herbal medicine fewer complications could be very appropriate alternative. Therefore in present study, we have examined properties ethanolic extract leaves mice using maximal electroshock seizers (MES)test, Pentylenetetrazole (PTZ), i...

Composite preparations based on rhamnolipid biosurfactants and N-containing heterocyclic 1,4-naphthoquinone derivatives were obtained. The formation of the compositions was confirmed by UV spectroscopy, dynamic light scattering changes in surface tension comparison with original solutions. Physicochemical biological properties composite drugs have been studied. anticonvulsant effect assessed us...