Perfusion analysis computes blood flow parameters (blood volume, blood flow, mean transit time) from the observed flow of contrast agent, passing through the patient’s vascular system. Perfusion deconvolution has been widely accepted as the principal numerical tool for perfusion analysis, and is used routinely in clinical applications. This extensive use of perfusion in clinical decision-making...

abstract objective: abnormal values of the transient ischemic dilation (tid) ratio are associated with severe and extensive coronary artery disease (cad). tid can be used as a diagnostic and prognostic marker of cad in diabetic patients. the aim of current study was to determine the pooled estimate of tid ratio in single myocardial perfusion scan in diabetic patients by a systematic review and ...

liver injury induced by viruses, chemicals and drugs can be protected by different medicinal plants. feijoa sellowiana (myrtaceae) is an evergreen bush native to southern areas of south america, as well as iran where the fruits are very popular. feijoa has shown a potent antimicrobial effect. morever, the antioxidant activity of total feijoa extract has also been reported. mdma or ecstasy is a ...

brain single-photon emission computerized tomography (spect), in particular, with perfusion agents or with neuroreceptor imaging radiopharmaceuticals, is rapidly becoming a clinical tool in many neurologic and psychiatric conditions. this imaging modality has been used for diagnosis, prognosis assessment, evaluation of response to therapy, risk stratification, detection of benign vs. malignant ...

objective: although coronary artery disease (cad) is the leading cause of death in type 2 diabetic patients, it is frequently asymptomatic. myocardial perfusion imaging (mpi) is reported to show ischemia in a significant number of asymptomatic diabetic patients. we studied the prevalence and severity of myocardial perfusion defects in asymptomatic diabetic patients and its clinical impact. meth...

Introduction: The ability to non-invasively measure tissue perfusion is critical for assessing the physiological functions of human skeletal muscle in both healthy and disease states. The traditional techniques to measure tissue perfusion in human muscle are invasive and measure only bulk properties which do not render information on either spatial or temporal heterogeneity. Velocity selective ...

AIM To measure the prevalence of abnormal rest perfusion in a population of consecutive patients with known hypertrophic cardiomyopathy (HCM) referred for cardiovascular MRI (CMR), and to assess any associations between abnormal rest perfusion and the presence, pattern, and severity of myocardial scar and the presence of risk factors for sudden death. MATERIALS AND METHODS Eighty consecutive ...

Background The clinical benefits of endovascular treatment in renal artery stenosis (RAS) remain controversial. This study used an intraoperative perfusion imaging technique, called flat-panel detector parenchymal blood volume (FD-PBV), to observe the change after RAS. Materials and methods In a prospective, single-center study, we assigned 30 patients with atherosclerotic RAS who underwent bet...

PURPOSE To quantitatively and qualitatively assess perfusion with pulse-inversion (PI) ultrasonography (US) in rabbit model of acute testicular ischemia. MATERIALS AND METHODS Institutional animal care committee approval was obtained. After 35 rabbits underwent unilateral spermatic cord occlusion, testicular Doppler US and contrast material-enhanced PI imaging were performed. Enhancement data...

OBJECTIVE Despite the increasingly broad use of perfusion applications, we still have no generally accessible means for their verification: The common sense of perfusion maps and "bona fides" of perfusion software vendors remain the only grounds for acceptance. Thus, perfusion applications are one of a very few clinical tools considerably lacking practical objective hands-on validation. MATER...