Monitoring of tissue perfusion is an essential step in the management of acute circulatory failure. The presence of cellular dysfunction has been a basic component of shock definition even in the absence of hypotension. Monitoring of tissue perfusion includes biomarkers of global tissue perfusion and measures for assessment of perfusion in non-vital organs. The presence of poor tissue perfusion...

To explore mechanisms of hypoxemia after acute pulmonary embolism, we measured regional pulmonary blood flow and alveolar ventilation before and after embolization with 780-micrometers beads in five anesthetized, mechanically ventilated pigs. Regional ventilation and perfusion were determined in approximately 2.0-cm3 lung volumes by using 1-micrometers-diameter aerosolized and 15-micrometers-di...

Introduction Perfusion is the term applied to capillary blood flow in tissue. Since the blood carries oxygen and nutrition to the tissue through the capillaries, perfusion is important in maintaining tissue viability. The study of brain perfusion has clinical applications due to the changes in perfusion associated with several neurological diseases. Diagnosis, lesion characterisation and follow...

  Introduction: Studies with single photon emission computed tomography (SPECT) have revealed inconsistent changes of regional cerebral blood flow (rCBF) in schizophrenia. Some studies investigated the rCBF and its relationship with psychopathology, positive and negative symptoms in treated patients. However, there is a little information about the pattern of rCBF in ...

The relationship between cardiac output (CO) and peripheral resistance (Rp) was examined under the following conditions for coronary perfusion: constant coronary flow perfusion; perfusion with a pressure equal to mean aortic pressure (AoP perfusion); and perfusion with a pressure equal to the mean AoP 30 mm Hg (AoP 30 mm Hg perfusion). We also examined the coronary pressure-flow relationship. F...

Perfusion refers to the delivery of oxygen and nutrients to tissues by means of blood flow and is one of the most fundamental physiological parameters. Disorders of perfusion also account for most of the leading causes of medical disability and mortality. While measurements of perfusion are of direct diagnostic value in vascular disorders, perfusion measurements also serve as biomarkers for a b...

BACKGROUND Diffuse coronary atherosclerosis is the substrate for plaque rupture and coronary events. Therefore, in patients with mild arteriographic coronary artery disease without significant segmental dipyridamole-induced myocardial perfusion defects, we tested the hypothesis that fluid dynamically significant diffuse coronary artery narrowing is frequently manifest as a graded, longitudinal,...