Background: There are some discrepancy in association between activity of rheumatoid arthritis (RA) and periodontitis. The aim of this study was to evaluate the periodontal status of outpatients with RA. Methods: The study was conducted in 2013-14 in a rheumatology clinic in Sari, north of Iran on 74 patients with RA. Evaluation of RA disease activity was according to disease activity score 28 ...

BACKGROUND AND OBJECTIVE Aggressive periodontitis is a rare and very severe periodontal disease of early onset, which is closely associated with Porphyromonas.gingivalis (P.g.) infection in the Japanese population. TLR2 encodes Toll-like receptor 2, which plays an important role in the protective response to P.g. infection. We investigated a possible association between TLR2 and aggressive peri...

BACKGROUND: Aggressive periodontitis (AgP) by definition is a group of rare, very destructive forms of periodontitis, usually manifests itself at an early age and shows a marked tendency to aggregate in families. A variety of factors, such as microbial, environmental and behavioral have been suggested as risk factors of Aggressive periodontitis. METHODS: Ten cases with clinical and radiological...

We aimed to systematically investigate the potential association of matrix metalloproteinase (MMP)-9, -3, -2, and -8 gene polymorphisms with susceptibility to periodontitis using meta-analysis. A literature search in PubMed, Embase, and Web of Science was conducted to obtain relevant publications. Finally a total of 16 articles with 24 case-control studies (nine on MMP-9-1562 C/T, seven on MMP-...

PURPOSE The aim of this paper is to assess the histopathological changes and the condition of oxidative stress in the saliva of the patients with periodontal disease. MATERIALS AND METHODS We have carried out our research on two groups of patients with periodontitis (a group of 16 patients with stage I periodontitis and a group of 16 patients with stage II periodontitis), who we have compared...

The detection of salivary biomarkers has a potential application in early diagnosis and monitoring of periodontal inflammation. However, searching sensitive salivary biomarkers for periodontitis is still ongoing. Oxidative stress is supposed to play an important role in periodontitis progression and tissue destruction. In this cross-sectional study, we investigated total antioxidant capacity (T...

AIM To determine the presence and location (stroma versus epithelium) of citrullinated proteins in periodontitis tissue as compared to non-periodontitis tissue and synovial tissue of RA patients. MATERIALS & METHODS Periodontitis, healthy periodontal and RA-affected synovial tissue samples were collected in addition to buccal swabs. These samples were stained for the presence of citrullinated...

OBJECTIVE Shortened leukocyte telomere length (LTL) and diagnosis of periodontitis are associated with an increased risk of complications and mortality in diabetes. This study investigated the association between LTL, endotoxemia, and severity of periodontitis in a large cohort of people with diabetes. RESEARCH DESIGN AND METHODS Six hundred thirty individuals (371 with type 2 and 259 with type...

Although the clinical relationship between periodontitis and diabetes mellitus (DM) is well established, few investigations have focused on the immunoinflammatory responses in sites with periodontitis in subjects with DM. Because of the potential association between periodontitis and diabetes, the aim of this study was to examine the serum levels of IL17 in diabetic and non-diabetic rats with e...

Periodontium consist of cementum, periodontal ligament and alveolar bone. The term periodontitis/periodontal disease represent a group of disease that affects the surrounding and supporting tissues of teeth. Periodontal disease can be broadly classified as gingival diseases (gingivitis) and periodontitis. Gingivitis presents as inflammation of the soft tissue surrounding the teeth and is charac...