It has been thought that adult nervous tissues show a remarkable degree of resistance to injury by x rays. Clemedson and Nelson (1960), after a comprehensive review of the literature, state: " Nervous tissues, especially of adult animals, show a remarkable radio-resistance." In the past few years, however, experimental work on animals (Lander, 1959; Innes and Carsten, 1961) suggests that delaye...

Peripheral neuropathy is a rare manifestation in hyperthyroidism. We describe the neurological manifestations of a 38 year old female with Graves' disease who developed peripheral neuropathy in the course of her treatment with propylthiouracil. After the drug was tapered off, the neurological signs disappeared. Therefore, we call attention for a possible toxic effect on peripheral nervous syste...

OBJECTIVE To describe the sensitivity, specificity, positive predictive value, and negative predictive value of vibration perception threshold (VPT) testing in subjects with type 1 diabetes relative to gold standard assessments of peripheral neuropathy. RESEARCH DESIGN AND METHODS VPT was determined in 1,177 adults with type 1 diabetes 13-14 years after participating in a study of intensive (...

OBJECTIVE To study the nerve conduction velocity in clinically undetectable and detectable peripheral neuropathy in type 2 diabetes mellitus with variable duration. MATERIAL AND METHODS This cross sectional study was conducted in diagnosed type 2 diabetes mellitus patients. They were divided in groups: Group I (n=37) with clinically detectable diabetic peripheral neuropathy of shorter duratio...

A 25-year-old woman with chronic neuropsychiatric symptoms, peripheral neuropathy and hypoglycaemia was found to have an islet cell adenoma in the pancreas. Her neuropsychiatric symptoms disappeared following its removal and she partially recovered from her peripheral neuropathy.

back ground: vincristine (vcr), is a chemotherapy drug, useful in the treatment of leukemia, lymphoma and solid tumor and it is a potent neurotoxin and sensory neuropathy drug which a common behavioral toxicity of this drug. neuropathy is common squeal of intensive chemotherapy protocols that contain vincristine and corticosteroids. materials and methods: this study was a retrospective and desc...

Neuropathy is associated with side effects of frontline chemotherapeutics, which is a prominent therapy utilized in prevalent cancers. Peripheral neuropathy negatively impacts quality of life in cancer patients and survivors. It also affects the dose plan of the treatment, thereby limiting the efficacy of the treatment. We searched the electronic database PubMed for pre-clinically and clinicall...

Introduction Ethambutol is a promising antituberculous drug which has been proposed as a replacement for PAS in the first-line triple therapy of tuberculosis. This suggestion is based on its equal or possible superior effectiveness in man, compared with PAS (Donomae & Yamamoto, 1966; Bobrowitz, 1966), whilst having few toxic effects in the doses at present recommended (Tubercle, 1966; Tiburtius...