The activity of five simulated antifungal regimens for eradication of catheter-related bloodstream Candida infection was evaluated with an in vitro pharmacodynamic model. Single-lumen central venous catheters were colonized with Candida species by sequentially incubating central venous catheters in plasma and then in growth medium (RPMI plus morpholinepropanesulfonic acid) containing a standard...

Medical science has made dramatic strides in the use of innovative drug therapies to improve the lives of patients with life-threatening and chronic illnesses. As new therapies have evolved, so has the way in which they are administered. The transition of care from hospital to home and cost competition forced the home infusion industry to find safe, cost-effective methods to deliver parenteral ...

Aim: This study was carried out to determine the nurses’ use of evidence-based applications for prevention complications related peripheral venous catheter (PVC) placement. Method: The conducted as a descriptive between March -June 2016 at medical, and surgical wards, intensive care units state hospital in western part Turkey. Hundred thirty nurses who agreed participate constituted sample size...

cerebral venous thrombosis, including thrombosis of cerebral veins and major dural sinuses, is an uncommon disorder in the general population. however, it has a higher frequency among patients younger than 40 years of age, patients with thrombophilia, pregnant patients or those receiving hormonal contraceptive therapy or has foreign body such as catheter in their veins or arterial system. in th...

OBJECTIVES Intraosseous access is a rapid and effective route of fluid and drug administration. Its use has been proven in emergency medicine, pediatrics, and the military. We aimed to assess its performance and utilization against landmark-guided central venous catheter placement during inpatient medical emergencies. DESIGN Prospective observational study. SETTING Eight hundred fifty-six-b...

BACKGROUND A central venous catheter enables the measurement of hemodynamic variations, such as accurate central venous pressure; catheter malposition may induce potentially fatal complications. This case report describes a rare central venous catheter tip malposition in the right internal mammary artery. CASE PRESENTATION A 56-year-old Japanese woman who presented with severe pneumonia secon...

OBJECTIVES We sought to validate a new noninvasive technique to determine central venous pressure (CVP) using high-resolution compression sonography. BACKGROUND Information concerning CVP is crucial in clinical situations, including cardiac failure, volume overload, and sepsis. The measurement of CVP, however, requires puncture of a vein with attendant risk of complication. METHODS After a ...

Introduction / objectives Bloodstream infections related to central venous catheter are the most frequent causes of morbidity and mortality in intensive care units. Studies show that education and training of health professionals on the practice of dealing with the central venous catheter is an important tool in preventing and reducing infections related to central venous catheter. The aim of t...

BACKGROUND Measurement of central venous pressure (CVP) is a reliable method for evaluating intravascular volume status and cardiac function; however it is an invasive and expensive method that may result in some complications such as arterial puncture, pneumothorax and development of infections. This study was performedto compare CVP measurements between central and peripheral catheters in inf...