Insulin and insulin-like growth factor I (IGF-I) both play important roles in vascular remodeling. Moreover, nitric oxide (NO) is well established as a counterregulatory agent that opposes the actions of several vascular agonists, in part by decreasing smooth muscle motility. We tested the hypothesis that NO blocks insulin or IGF-I-induced rat aortic smooth muscle cell motility via a mechanism ...

Present tooth-bleaching techniques are based upon hydrogen peroxide as the active agent. It is applied directly, or produced in a chemical reaction from sodium perborate or carbamide peroxide. More than 90% immediate success has been reported for intracoronal bleaching of non-vital teeth, and in the period of 1-8 years' observation time, from 10 to 40% of the initially successfully treated teet...

BACKGROUND Antibacterial activity of honey is mainly dependent on a combination of its peroxide activity and non-peroxide components. This study aims to investigate antibacterial activity of five varieties of Malaysian honey (three monofloral; acacia, gelam and pineapple, and two polyfloral; kelulut and tualang) against Staphylococcus aureus, Bacillus cereus, Escherichia coli, and Pseudomonas a...

In this and following papers, the properties of two new catalytically active enzyme-substrate compounds of catalase are given. Paper I gives spectroscopic data, Paper II and III, data on kinetics and activity, and, in Paper IV, the reactions of these enzyme-substrate compounds with hydrogen peroxide are discussed. The red catalase ethyl hydrogen peroxide compound studied by Stern (1) is charact...

In this and following papers, the properties of two new catalytically active enzyme-substrate compounds of catalase are given. Paper I gives spectroscopic data, Paper II and III, data on kinetics and activity, and, in Paper IV, the reactions of these enzyme-substrate compounds with hydrogen peroxide are discussed. The red catalase ethyl hydrogen peroxide compound studied by Stern (1) is charact...

The present review summarizes publications on the artemisinin peroxide fragment synthesis from 1983 to 2016. The data are classified according to the structures of a precursor used in the key peroxidation step of artemisinin peroxide cycle synthesis. The first part of the review comprises the construction of artemisinin peroxide fragment in total syntheses, in which peroxide artemisinin ring re...

Peroxiredoxins are important hydroperoxide detoxification enzymes, yet have only come to the fore in recent years relative to the other major players in peroxide detoxification, heme-containing catalases and peroxidases and glutathione peroxidases. These cysteine-dependent peroxidases exhibit high reactivity with hydrogen peroxide, organic hydroperoxides, and peroxynitrite and play major roles ...

BACKGROUND Bleaching treatments decrease shear bond strength between orthodontic brackets and teeth; although definite results have not been reported in this regard. OBJECTIVES This study determined the effects of different bleaching protocols on the shear bond strength of orthodontic brackets to teeth. MATERIALS AND METHODS This experimental study was performed in Iran. Forty-eight extract...

The irreversible inhibition of catalase by 3-amino-l, 2,4-trizole and a group of related inhibitors (1) in the presence of a continuous supply of hydrogen peroxide has been shown to result from a reaction of the inhibitors with catalase-hydrogen peroxide complex I (2) in which 1 mole of inhibitor is incorporated into the enzyme protein for each mole of catalase heme that has reacted (1). The ki...