PURPOSE To delineate the molecular mechanisms underlying autosomal dominant congenital cataracts caused by a 5 bp duplication in human CRYGC. METHODS c.119_123dup (CRYGC5bpd) and wild-type human γC-crystallin (CRYGC) were expressed in transgenic mouse lenses by the chicken βB1-crystallin promoter. Lenses were characterized histologically, by real-time PCR, SDS-PAGE, and Western blot. pET and ...

Objective(s): To investigate the diagnostic accuracy of positron emission mammography (PEM) and positron emission tomography/computed tomography (PET/CT) for small breast tumors of less than 20 mm in size.Methods: The study was conducted on a total of 100 subjects (i.e., 50 patients with pathologically proven breast cancer and 50 normal cases of medical screening). The total number of tumors wa...

Until recently PET scanning has been available only at major universities or teaching hospitals possessing the necessary resources and expertise to operate a research PET facility. Most dedicated PET centers cost several millions of dollars, and include a cyclotron, a radiochemistry laboratory to synthesize PET radiopharmaceuticals, a multicrystal dedicated PET camera, advanced computer f...

Background: To retrospectively describe imaging characteristics of liver metastases on fused FDG-PET/ MRI data sets and to compare the diagnostic accuracy of MRI and fused FDG-PET/MRI data sets for the detection of liver metastases in patients undergoing systemic anticancer treatment. Materials and Methods: 43 oncological patients (mean age: 56+/- 11 years) were investigated by FDG-PET...

during the last decades a new class of materials named fiber/metal laminates (fmls) was introduced. it is a hybrid composite consisting of alternating thin layers of metal sheets and fiber-reinforced composite material. fmls have both low weight and good mechanical properties. in this study, the impact behavior of this attractive material is investigated. the effect of fiber angle, stacking seq...

The objectives of this study were to determine the chemical composition and nutritive value of corn protein product 1 (CPP 1), corn protein product 2 (CPP 2), and corn fiber (CF), novel coproducts of the ethanol industry, and compare these feed ingredients with standard plant protein ingredients [soybean meal (SBM), distillers dried grains with solubles (DDGS), corn gluten meal (CGlM), and corn...

The phenomenon of separation into constituent layers connecting the core and laminate a composite sandwich complex is vital complication that leads to early failure such material. direction construction's exfoliation rigidity increased between interlaminar low fiber augmentation. bioinspired technique hybrid material was used on an aluminium face sheet with interlayer composition PET foam glass...