The reconstruction of PET brain data in a PET/MR hybrid scanner is challenging in the absence of transmission sources, where MR images are used for MR-based attenuation correction (MR-AC). The main challenge of MR-AC is to separate bone and air, as neither have a signal in traditional MR images, and to assign the correct linear attenuation coefficient to bone. The ultra-short echo time (UTE) MR...

A critical step in radiotherapy treatment planning process is to accurately locate the tumor and determine its extent. Variability in gross tumor volume (GTV) delineation is a major source of systematic error in conformal radiotherapy. CT scan is the principle source of imaging data used for defining GTV for planning conformal therapy. CT is widely available less costly and compatible with radi...

The present thesis is focused on the development and application of narrow scanned high energy photon beams for radiation therapy. The introduction of physically and biologically optimized intensity modulated radiation therapy (IMRT) requires a flexible and accurate dose delivery method to maximize the treatment outcome. Narrow scanned photon beams is a fast option for IMRT since it is not depe...

To the Editor: Advanced renal cell carcinoma (RCC) has a poor prognosis when surgically untreatable. Medical treatment remains unsatisfactory. Target therapies may provide alternative options and, among them, sorafenibmay improve the progression-free survival compared with standard treatment1,2. We report a complete clinical response following sorafenib treatment in a 74year-old man with thyroi...

Lymphoma presenting with enlarged adrenal glands is not common. According to the literature, most adrenal lymphomas do not have extra-adrenal sites. We examined a 47-year-old male patient because of abdominal pain-an unusual presentation of adrenal lymphoma. Following ultrasonographic examination that showed bilateral massively enlarged adrenal glands, the patient underwent F-18 FDG PETCT. Writ...

Meningiomas with distant metastases rarely occur. We report a patient with coincident primary lung cancer and metastatic meningiomas. The presence of distinct imaging features and a differential response to chemotherapy enabled us to distinguish the primary lung cancer from the metastatic lesions. Previous studies suggest that several factors can enhance the propensity of meningioma for metasta...

Background Treatment of patients with Takayasu arteritis (TAK) is challenging in-spite the use conventional cytotoxic agents and biologics. Tofacitinib has been reported to be effective in inducing maintaining remission around 80% refractory TAK [1]. Objectives To assess efficacy safety tofacitinib Indian TAK. Methods In this retrospective study, medical records consecutive being treated either...