BACKGROUND Pharmaceutical companies are prohibited from marketing medications for off-label uses in both the United States and Canada. In the United States, there have been several recent multi-billion dollar settlements with pharmaceutical companies based, partly, on off-label promotion. Health Canada has not publicized any investigations into, or prosecutions of, pharmaceutical companies for ...

Clinical trial allocation in multinational pharmaceutical companies includes country selection and site selection. With emphasis on site selection, the overall aim of this study was to examine which factors pharmaceutical companies value most when allocating clinical trials. The specific aims were (1) to identify key decision makers during country and site selection, respectively, (2) to evalua...

Objectives To identify the policies of major pharmaceutical companies on transparency of trials, to extract structured data detailing each companies' commitments, and to assess concordance with ethical and professional guidance.Design Structured audit.Setting Pharmaceutical companies, worldwide.Participants 42 pharmaceutical companies.Main outcome measures Companies' commitments on sharing summ...

The present study aims to identify the financial strengths and weaknesses of the Indian public sector pharmaceutical enterprises by properly establishing relationships between the items of the balance sheet and profit and loss account. The study covers two public sector drug and pharmaceutical enterprises listed on BSE. The study has been undertaken for the period of twelve years from 1997-98 t...

The total global pharmaceutical market was estimated at around US $343 billion (bn) in 1999 and registered a 10% growth in 1999 compared to 6-7% p.a. in the past three years. The industry is characterised by high fragmentation with the top ten companies accounting for only around 36% of the prescription pharmaceutical market in 1998. However, consolidation in the industry has resulted in an inc...

todays, the parent company has a great role in managing and monitoring subsidiaries and companies in promoting their industrial activities. but, the main problem for pharmaceutical parent companies is the lack of clarity and confusion of responsibilities between units. successful parenting needs to create the element of 'fit' between the ways parent operates – parent characteristics –...

The field of automated patch-clamp electrophysiology has emerged from the tension between the pharmaceutical industry's need for high-throughput compound screening versus its need to be conservative due to regulatory requirements. On the one hand, hERG channel screening was increasingly requested for new chemical entities, as the correlation between blockade of the ion channel coded by hERG and...