The promotion of pharmaceutical products on the internet, an unforeseen event only a few years ago, has begun. While some companies only have registered domain sites with Internic, others have set up home pages that deal with pharmaceutical products such as Rogaine (minoxidil), a drug product approved to promote the growth of hair; Claritin (loratidine), a prescription nonsedating antihistamine...

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Sheng-Mai-San is a multi-component traditional Chinese herbal preparation. Due to the fact granulated additives, such as starch, carboxymethyl cellulose, lactose and raw herbal powder may alter the content of the bioactive markers in the herbal products, a developed ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) method was used to measure the herbal biomarke...

Pharmaceutical products are indispensable for improving health outcomes. An extensive body of work on access to and use of medicines has resulted in an assortment of tools measuring various elements of pharmaceutical systems. Until now however, there has been little attempt to conceptualize a pharmaceutical system as an entity and define its strengthening in a way that allows for measuring syst...

Background: There is growing interest in the natural and constructed wetlands for wastewater treatment. While nutrient removal in wetlands has been extensively investigated, information regarding the degradation of the pharmaceuticals and personal care products (PPCPs) has only recently been emerging. PPCPs are widely distributed in urban wastewaters and can be removed to some extent by the con...

OBJECTIVE To assess whether new pharmaceutical products approved by the United States Food and Drug Administration (FDA) in 2011 and 2012 were registered, commercialized and sold at affordable prices in the Latin American countries where they were tested. METHODS We obtained a list of new molecular entities (new pharmaceutical products) approved by the FDA in 2011 and 2012. FDA medical review...

Sterility test is an established method for detecting the presence of viable forms of microorganisms in or on finished pharmaceutical products. Sterility, in this sense, means that a product is free from viable microorganisms (although not necessarily metabolic by-products or toxins). The classic form sterility test examines a pharmaceutical product in contact a culture medium, as a way of dete...

The greater consciousness awakened in recent years on healthy and organic has led to increase “natural” products demand worldwide. The quality and high content on bioactive compounds have consolidated their penetration in cosmetic and food market, showing great potential within the pharmaceutical sector too. For this reason, food, cosmetic and pharmaceutical sectors have been forced to develop ...

Atorvastatin reduces morbidity and mortality due to cardiovascular events. This study was conducted to assess the prices and pharmaceutical quality of innovator atorvastatin 20 mg with its locally available generics in Palestine and to assess the suitability of their interchangeability. The prices of innovator and generic atorvastatin 20 mg were determined and compared. Innovator atorvastatin a...

Objective. The marketing authorization of generic and similar pharmaceutical drug products involves the analysis of proposing company's administrative aspects as well as drug product technical description and scientific evaluations. This study evaluated the main reasons for registration refusal of generic and similar pharmaceutical drug products in Brazil. The aim is to help future applicants t...