OBJECTIVES To evaluate the cost effectiveness of onabotulinumtoxinA (BOTOX(®), 200 units [200 U]) for the management of urinary incontinence (UI) in adults with neurogenic detrusor overactivity (NDO) due to subcervical spinal cord injury or multiple sclerosis that is not adequately managed with anticholinergic drugs (ACHDs). PERSPECTIVE UK National Health Service (NHS) perspective. METHODS ...

We previously demonstrated that bovine subcutaneous preadipocytes promote adipogenic gene expression in muscle satellite cells in a co-culture system. Herein we hypothesize that saturated fatty acids would promote adipogenic/lipogenic gene expression, whereas mono- and polyunsaturated fatty acids would have the opposite effect. Bovine semimembranosus satellite cells (BSC) and intramuscular prea...

BACKGROUND The successful utilization of the balanced scorecard (BSC) framework in health care has been demonstrated in the literature. Given these successes, a financially struggling hospital implemented a BSC framework intervention which attempted a culture change centered upon patient satisfaction which it hoped would translate to improved financial stability. Despite the evidence of BSC suc...

Recent studies have highlighted the role of multisensory integration as a key mechanism of self-consciousness. In particular, integration of bodily signals within the peripersonal space (PPS) underlies the experience of the self in a body we own (self-identification) and that is experienced as occupying a specific location in space (self-location), two main components of bodily self-consciousne...

The intestinal nematode Baylisascaris schroederi is an important cause of death for wild and captive giant pandas. Inorganic pyrophosphatases (PPases) are critical for development and molting in nematode parasites and represent potential targets for vaccination. Here, a new PPase homologue, Bsc-PYP-1, from B. schroederi was identified and characterized, and its potential as a vaccine candidate ...

Biological soil crusts (BSCs) cover >35% of the Earth's land area and contribute to important ecological functions in arid and semiarid ecosystems, including erosion reduction, hydrological cycling, and nutrient cycling. Artificial rapid cultivation of BSCs can provide a novel alternative to traditional biological methods for controlling soil and water loss such as the planting of trees, shrubs...

2013;26(4) S Afr J Clin Nutr Ogunkunle MO, BSc, MSc, Assistant Lecturer Department of Human Nutrition, University of Ibadan, Nigeria Oludele AS, BSc, Lecturer Department of Home Economics, Osun State College of Education, Ila Orangun, Nigeria Correspondence to: Ogunkunle Morenike, e-mail: [email protected]

Comparative Lipidomics Profiling of Human Atherosclerotic Plaques Christin Stegemann, PhD; Ignat Drozdov, MSc; Joseph Shalhoub, BSc, MBBS, MRCS; Julia Humphries, PhD; Christophe Ladroue, PhD; Athanasios Didangelos, PhD; Mark Baumert, BSc; Mark Allen, PhD; Alun H. Davies, MA, DM, FRCS, FHEA; Claudia Monaco, MD, PhD; Alberto Smith, PhD; Qingbo Xu, MD, PhD; Manuel Mayr, MD, PhD Clinical Perspectiv...

E-business is far more about strategy than technology (Raisinghani & Schkade, 2001). An effective e-business strategy is concerned with e-business multidimensional characteristics associated with different levels, parties, elements, and growth pattern features (Bakry & Bakry, 2001). In the process, the strategy must incorporate the effects of the instant and global Internet communication mechan...

The paper focuses on the use of Fuzzy Cognitive Mapping (FCM) in Balanced Scorecard (BSC) performance measurement framework. We present a state art areas and BSC. highlight limitations BSC frameworks drawbacks identified strategic maps. then FCM algorithm its decision making as solution to drawbacks. elaborate an methodology supporting software application called Modeler for development hierarc...