Objective. To investigate dynamic properties of age trajectories of physiological indices and their effects on mortality risk and longevity using longitudinal data on more than 5,000 individuals collected in biannual examinations of the Framingham Heart Study (FHS) original cohort during about 50 subsequent years of follow up. Methods. First we performed empirical analyses of the FHS longitudin...

BACKGROUND Individuals with Mibyeong are difficult to identify. Although extensive research has attempted to introduce an easy and clear method for Mibyeong diagnosis, the indices used to categorize Mibyeong severity are unclear. We hypothesized that individuals with severe Mibyeong have reduced physiological function, thus activating homeostatic regulatory functions and inducing alterations in...

Tests of pulmonary mechanical function provide information about the state of the lungs, both airways and parenchyma. This information can be extracted from measurements made in experimental animals, especially the combined determination of pulmonary resistance and dynamic compliance. This report discusses the rationale upon which effects of an intervention on the lung periphery can be distingu...

We have developed a new method to estimate no only stress occurrence, but also various workplace stress types. The method relies on adaptive selection of physiological indices integrated into an intelligent multisteps discrimination process. Preliminary results revealed the method promising to improve estimation accuracy of workplace stress types. The study reported here, has two purposes: inve...

Two sessions of relaxation instructions were administered under high and low expectancy conditions. Fifty-four college students scoring high on a self-report measure of anxiety served as subjects. Live and taped abbreviated progressive muscle relaxation instructions and a self-relaxation condition were equally effective in reducing within-session self-report and physiological indices of anxiety...

In deriving clinically used hemodynamic indices such as fractional flow reserve and coronary flow velocity reserve, simplified models of the coronary circulation are used. In particular, myocardial resistance is assumed to be independent of factors such as heart contraction and driving pressure. These simplifying assumptions are not always justified. In this review we focus on distensibility of...

The objective of this study was to identify a parsimonious set of physiological measures that could be used to best predict cognitive fatigue levels. A 37 hour sleep deprivation study was conducted to induce reduced levels of alertness and cognitive impairment as measured by a psychomotor vigilance test. Non-invasive, wearable and ambulatory sensors were used to acquire cardio-respiratory and m...