Psoriasis is a disease involving the innate and adaptative components of immune system, it triggered by environmental factors in genetically susceptible individuals. However, its physiopathology not fully understood yet. Recent technological advances, especially genome epigenome-wide studies, have provided better understanding genetic epigenetic mechanisms to determine psoriasis facilitate deve...

Diabetic neuropathy is a common complication of both type 1 and type 2 diabetes, which affects over 90% of the diabetic patients. Although pain is one of the main symptoms of diabetic neuropathy, its pathophysiological mechanisms are not yet fully known. It is widely accepted that the toxic effects of hyperglycemia play an important role in the development of this complication, but several othe...