Objective: To evaluate the synergistic effect of antimicrobial plant extracts from traditional medicinal plants on standard microorganism strains. Method: In the present study, eight plants (extracted with five different solvents) were screened for antibacterial activity against four gram negative and four gram positive strains by micro-broth dilution assay. Afterward, antimicrobial chloroform ...

The Catharanthus roseus L. plant leaf extracts were prepared by using solvents such as acetone, ethanol, and chloroform and tested against pathogenic microorganisms to determine their antimicrobial potential. Catharanthus roseus leaf extracts showed maximum antibacterial activity against all the pathogenic microorganisms. Among the solvents tested, ethanol showed maximum antibacterial activity ...

Fourteen plant species collected in Iran and selected mainly on the basis of their antimicrobial and/or antifungal activities were evaluated for in vitro antiplasmodial and cytotoxic effects in a study designed to screen plant extracts with selective activity against Plasmodium falciparum. The methanol extracts of nine of the species tested exhibit activity against Plasmodium falciparum (MIC va...

There is cumulative resistance against antibiotics of many bacteria. Therefore, the development of new antiseptics and antimicrobial agents for the treatment of skin infections is of increasing interest. We have screened six plant extracts and isolated compounds for antimicrobial effects on bacteria and yeasts with dermatological relevance. The following plant extracts have been tested: Gentian...

This study was designed to evaluate the hypoglycemic effects of different plant extracts in single and in combined formulation, in experimentally induced "diabetic rabbits". The extracts were obtained from seeds of Syzygium jambolana, fruits of Momordica charantia and leaves of Azadirachta indica. Treatment of diabetes with plant extracts was started at 8 days after alloxan injection. Rabbits w...

the formation of hemozoin (malaria pigment) has been proposed as an ideal drug target for antimalarial screening programs. in this study, we used an improved, cost-effective and high-throughput spectrophotometric assay to screen plant extracts for finding novel antimalarial plant sources. fifteen extracts with different polarity from three iranian artemisia species, a. ciniformis, a. biennis an...

there is the need for new drugs with better action and lesser side effects. a lot of research is being undertaken to find out new plant drugs, their extraction and pharmacological evaluation. one of such plant is curcuma aromatica whichbelongs to the genus curcuma and reported to have high ethno-botanical values in traditional medicine. the present study evaluates comparative pharmacological ac...

plants are potent biochemists; biologically active compounds present in the medicinal plants have always been ofgreat interest to scientists working in this field. thus, the aim of the current study was to screen the antimicrobial activity of acacia nilotica, ziziphus mauritiana, bauhinia variegate and lantana camara against some selected clinical isolated strains. although previous studies hav...

The present study was carried out to evaluate the antidiabetic activity of Vinca rosea methanolic whole plant extracts in alloxan induced diabetic rats for 14 days. The methanolic whole plant extract at high dose (500 mg/kg) exhibited significant anti-hyperglycemic activity than whole plant extract at low dose (300 mg/kg) in diabetic rats. The methanolic extracts also showed improvement in para...

costus speciosus (koen) j.e. sm. plant and its extracts are used for treatment of fever, snake bites, jaundice, and as a purgative, astringent and antibacterial agent. in the present study, an attempt has been made to evaluate in vitro antioxidant activity of different extracts of this plant by dpph radical scavenging activity, total antioxidant capacity, nitric oxide scavenging activity, ion c...