HIV is the etiological agent of AIDS that has created major health care problem throughout the world. The aim of the present study is to evaluate the cytotoxic effects and anti-HIV activity of Phyllanthus niruri whole plant extracts. Hexane, chloroform, ethyl acetate, acetone and methanol solvents were used to prepare the extracts by sequential maceration method. RetroSys HIV-1 RT (Innovagen, S...

Background:Oncoba spinosa, an endangered medicinal plant whose secondary metabolites have not been extensively profiled, and which is hitherto yet to be examined for cytotoxicity, is being investigated in this study. Methods: Leaves of Oncoba spinosa (800 g) were extracted with 95% aqueous methanol. The crude extract was partitioned with n-hexane and the resultant defatted extract was extensive...