The clinical management of large-size cartilage lesions is difficult due to the limited regenerative ability of the cartilage. Different biomaterials have been used to develop tissue engineering substitutes for cartilage repair, including chitosan alone or in combination with growth factors to improve its chondrogenic properties. The main objective of this investigation was to evaluate the bene...

EFFICACY OF INTRAUTERINE INSTILLATION AUTOLOGOUS PLATELET-RICH PLASMA ON ENDOMETRIAL GROWTH DURING THE FROZEN-THAWED EMBRYO TRANSFER CYCLES

There has been significant growth and advancement since, the last few decades in use of platelet its derivatives dentistry predominantly oral surgery periodontology. Very little is known about same orthodontics. emerging literature on platelets Platelets being reservoir cytokines factors plays a crucial role various regenerative processes. This review attempts to summarise concerning applicatio...

Platelet-rich plasma (PRP) is obtained from a patient’s own peripheral blood, after centrifuging it, and has growth factors.[1] There are clinical studies indicating that PRP therapy may enhance muscle or tendon healing, and it accelerates the tissue regeneration after musculoskeletal injuries such as strain or contusion, during sports activities.[1,2] The application of these products is docum...

       Mefloquine (MFQ), as a racemic mixture is used for the prophylaxis and treatment of malaria. Stereoselective pharmacodynamic and pharmacokinetic differences have been observed for MFQ. In the present study, the human blood was spiked with racemic MFQ. The concentration of MFQ enantiomers in various blood fractions including packed erythrocyte layer, platelet rich plasma and platelet poor...

Platelet-rich plasma (PRP) has gained growing popularity in the treatment of articular cartilage lesions in the last decade. However, the potential harmful effects of leukocytes in PRP on cartilage regeneration have seldom been studied in vitro, and not at all in vivo yet. The objective of the present study is to compare the effects of leukocyte- and platelet-rich plasma (L-PRP) and pure platel...