The adhesive interaction between tumor cells and the host cells or the extracellular matrix plays a crucial role in tumor metastasis. To evaluate the mediation of cell adhesion by Daphne mucronata, an anti-cancer medicinal plant in Iranian folk medicine, the adhesion of thrombin activated human platelets to the cultured monocytes or HL-60 cells was investigated under the effect of the plant ext...

background: the level of platelet volume (mpv) has been reported to be a laboratory marker in inflammatory cases. objectives: the aim of this study was to seek whether mpv has a role in the diagnosis of acute appendicitis. it was also aimed to show the relationship of mpv with leukocyte count and c-reactive protein (crp) level. materials and methods: this study was conducted via retrospective a...

Introduction: In this study the evaluation of a Platelet-based Maximum Penalized Likelihood Estimation (MPLE) for denoising SPECT images was performed and compared with other denoising methods such as Wavelets or Butterworth filtration. Platelet-based MPLE factorization as a multiscale decomposition approach has been already proposed for better edges and surfaces representation due to Poi...

introduction: it has been reported that platelets can eradicate tumor cells in vitro, although the mechanism of this effect has not been determined. the effect of platelets on the induction of apoptosis in tumor cells is largely unknown. materials and methods: to investigate this effect, two human hematologic cell lines, k562 and daudi, were independently faced with unstimulated and thrombin-ac...

a preterm female baby with birth weight of 1.5kg was referred to our hospital on day 6 for difficulty in breathing. baby was admitted at birth for respiratory distress and feed intolerance to other hospital and in view of clinical deterioration baby was referred. baby had thrombocytopenia with platelets counts of 11000/ mm3 and high crp titer. baby had petechial haemorrhagic spots all over the ...

introduction: acute idiopathic thrombocytopenic purpura (itp) is an autoimmune bleeding disorder of childhood caused by production of auto antibodies against platelets. the aim of the present study was to compare the efficacy of intravenous immunoglobulin (ivig) and intravenous anti-d(iv anti-d) in itp treatment. methods and materials: in a clinical trial, 43 children with acute itp referred to...

Abstract Objectives The article presents the results of an in vitro study aimed at identifying changes parameters oxidative stress – concentration malondialdehyde (MDA), enzymatic activity superoxide dismutase (SOD-1) and protective antioxidant role melatonin (MLT) during exposure blood platelets to electromagnetic radiation (EMR) emitted by monitors. Methods Platelets were exposed EMR for 30- ...

Introduction: It has been reported that platelets can eradicate tumor cells in vitro, although the mechanism of this effect has not been determined. The effect of platelets on the induction of apoptosis in tumor cells is largely unknown. Materials and methods: To investigate this effect, two human hematologic cell lines, K562 and Daudi, were independently faced with unstimulated and thromb...