Poly(L-lactic acid) (PLLA) is a biodegradable plastic and one of the most famous plastics made from biobased materials. However, its physical strength is insufficient compared to general-purpose plastics. In this study, the effect of methylcyclodextrin (MeCD) addition on the structure and physical properties, especially the drawing behavior, of PLLA was investigated. Through thermal analysis, i...

By reaction of poly(L-lactic acid) (PLLA) membrane with 1,6-hexanediamine, free amino groups were introduced onto a PLLA surface, through which biocompatible macromolecules such as gelatin, chitosan, or collagen were covalently immobilized by employing glutaraldehyde as a coupling agent. The existence of free amino groups on the aminolyzed PLLA surface was verified quantitatively by the ninhydr...

For the purpose of obtaining high bone forming efficacy, development of chitosan was attempted as a tool useful as a scaffolding device. Porous chitosan matrices, chitosan-poly(L-lactide) (PLLA) composite matrices and chitosan coated on PLLA matrices were dealt with in this research. Porous chitosan matrix was fabricated by freeze-drying and cross-linking aqueous chitosan solution. Porous chito...

Poly(L-lactide) (PLLA) is a semicrystalline thermoplastic which belongs to a biocompatible, biodegradable and bioresorbable polymers. PLLA also fulfills many requirements of the traditional nonbiodegradable packaging materials and it is therefore considered of great value from an ecological point of view due to its biobased character. Nonetheless, there are several aspects such as its slow crys...

The modified poly(L-lactic acid) (PLLA) with different contents (0.5−3 wt %) of N,N’-bis(phenyl) 1,4-naphthalenedicarboxylic acid dihydrazide (NAPH) were prepared to evaluate effects NAPH on melt-crystallization behavior (DSC), thermal degradation (TGA) and mechanical properties PLLA. results demonstrated that as a heterogeneous organic nucleating agent enhanced crystallization ability PLLA in ...

Poly (3-hydroxy butyrate) (PHB), cellulose nano crystal (CNC) and a plasticizer (TBC) are mixed together with PLLA with the aim to increase the elongation at break for use in the food packing sector. Spherical (CNC) and fibril nano crystal (CNF) were prepared by hydrolysis of microcrystalline cellulose (MCC) in distilled water, and then stirred using a magnetic stirrer for 15 days and ultrasoni...

Poly(l-lactide) (PLLA) is the structural material of the first clinically approved bioresorbable vascular scaffold (BVS), a promising alternative to permanent metal stents for treatment of coronary heart disease. BVSs are transient implants that support the occluded artery for 6 mo and are completely resorbed in 2 y. Clinical trials of BVSs report restoration of arterial vasomotion and eliminat...

Tissue engineering is a rapidly growing technological area for the regeneration and reconstruction of damage to the central nervous system. By combining seed cells with appropriate biomaterial scaffolds, tissue engineering has the ability to improve nerve regeneration and functional recovery. In the present study, mouse induced pluripotent stem cells (iPSCs) were generated from mouse embryonic ...

the amphiphilic graft copolymer using chitosan (cs) as hydrophilic segment and poly (l-lactic acid) (plla) as hydrophobic segment, was prepared through a protection-graft-de protection route. chitosan is a polysaccharide comprising of copolymers of glucosamine and n-acetyl glucosamine. chitosan is the deacetylated derivative of chitin, which is one of the most abundant natural polysaccharides c...

The development of an artificial bone graft which can promote the regeneration of fractures or diseased bones is currently the most challenging aspect in bone tissue engineering. To achieve the purpose of promoting bone proliferation and differentiation, the artificial graft needs have a similar structure and composition of extracellular matrix. One-step electrospinning method of biocomposite n...