White matter ischemia is difficult to quantify histologically. Myelin-associated glycoprotein (MAG) is highly susceptible to ischemia, being expressed only adaxonally, far from the oligodendrocyte cell body. Myelin-basic protein (MBP) and proteolipid protein (PLP) are expressed throughout the myelin sheath. We compared MAG, MBP, and PLP levels in parietal white matter homogenates from 17 vascul...

The proteolipid protein gene products DM-20 and PLP are adhesive intrinsic membrane proteins that make up >/=50% of the protein in myelin and serve to stabilize compact myelin sheaths at the extracellular surfaces of apposed membrane lamellae. To identify which domains of DM-20 and PLP are positioned topologically in the extracellular space to participate in adhesion, we engineered N-glycosylat...

Centrosomes comprise a pair of centrioles surrounded by a matrix of pericentriolar material (PCM). In vertebrate cells, Pericentrin plays an important part in mitotic PCM assembly, but the Drosophila Pericentrin-like protein (PLP) appears to have a more minor role in mitotic fly cells. Here we investigate the function of PLP during the rapid mitotic cycles of the earlyDrosophila embryo. Unexpec...

Nearly all amputees continue to feel their missing limb as if it still existed, and many experience chronic phantom limb pain (PLP). What is the origin of these sensations? There is currently a broad consensus among investigators that PLP is a top-down phenomenon, triggered by loss of sensory input and caused by maladaptive cortical plasticity. We tested the alternative hypothesis that PLP is p...

Mel Frequency Cepstral Coefficients (MFCC) and Perceptual Linear Prediction (PLP) are the most popular acoustic features used in speech recognition. Often it depends on the task, which of the two methods leads to a better performance. In this work we develop acoustic features that combine the advantages of MFCC and PLP. Based on the observation that the techniques have many similarities, we rev...

Program Pengalaman Lapangan (School Internship Program), abbreviated as PLP, is an obligatory course in the curriculum of study programs under faculty teachers training and education. It adopts experiential field learning to provide comprehensive, direct, real experiences school. A long-term goal set develop professional teacher competencies. In Covid-19 pandemic, PLP has been implemented onlin...

BACKGROUND No large-scale, population-based study has considered the descriptive epidemiology of vitamin B-6 status with use of plasma pyridoxal 5'-phosphate (PLP), the indicator of vitamin B-6 adequacy used to set the current Recommended Dietary Allowance, which is < or = 2 mg/d for all subgroups. OBJECTIVES We sought to examine the epidemiology of vitamin B-6 status in the US population. ...

Using a human keratinocyte model of tumor progression, we have examined the regulation of gene expression and secretion of a parathyroid hormone-like peptide (PLP) that has been implicated in the pathogenesis of hypercalcemia in cancer. A rapid and transient induction of PLP mRNA in response to serum stimulation was demonstrated in both established (HPK1A) and malignant (Ill'KI A-rav) cells; ho...

Most SSDs (solid-state drives) use an internal DRAM (Dynamic Random Access Memory) to improve the I/O performance and extend SSD lifespan by absorbing write requests. However, this volatile memory does not guarantee persistence of buffered data in event sudden power-off. Therefore, highly reliable enterprise employ power-loss-protection (PLP) logic ensure durability using back-up power capacito...

A search of a mouse expressed sequence tag database for novel messenger RNAs (mRNAs) in the PRL/GH family has identified three clones that are homologous to the rat PRL-like protein A (PLP-A), PRL-like protein B (PLP-B), and decidual/trophoblast PRL-related protein (d/tPRP). Full-length complementary DNA clones for each of these three mouse mRNAs have been sequenced. Mouse PLP-A is predicted to...