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objective(s)cpg oligodeoxynucleotides (cpg odns) have been shown to have potent immunostimulatory adjuvant activity for a wide range of antigens. due to susceptibility of phosphodiester cpg odns (po cpg) to nuclease degradation, nuclease-resistant phosphorothioate cpg odns (ps cpg) were currently utilized in an in vivo model. in this study, according to some recently reported drawbacks with ps ...

In 2001, S. Bulman-Fleming et al. initiated the study of three flatness properties (weakly kernel flat, principally weakly kernel flat, translation kernel flat) of right acts AS over a monoid S that can be described by means of when the functor AS ⊗ − preserves pullbacks. In this paper, we extend these results to S-posets and present equivalent descriptions of weakly kernel po-flat, principally...

To investigate the differential contribution of oxidative and substrate-level phosphorylation to force production during repetitive, maximal tetanic contractions, single skeletal muscle fiber performance was examined under conditions of high-oxygen availability and anoxia. Tetanic force development (P) was measured in isolated, single type-1 muscle fibers (fast twitch; n = 6) dissected from Xen...

BACKGROUND Ambulatory oxygen is an important component of long-term oxygen therapy. Pulse-dose technology conserves oxygen and thus increases the operation time of a portable oxygen system. METHODS We tested 4 ambulatory oxygen systems (Helios, HomeFill, FreeStyle, and the compressed-oxygen cylinder system we regularly provide for long-term oxygen therapy at our Veterans Affairs hospital) wit...

BACKGROUND The effect of nail polish on pulse oximetry measurements in non-hypoxic subjects has been studied extensively. Some studies found that nail polish decreased pulse-oximetry (S(pO(2))) values, whereas others found no effects from nail polish. OBJECTIVE To determine if nail polish affects S(pO(2)) measurements in mildly hypoxic subjects. METHODS At high altitude, 5 investigators, wh...

BACKGROUND Pulse oximetry alone has been suggested to determine which patients on home mechanical ventilation (MV) require further investigation of nocturnal gas exchange. In patients with neuromuscular diseases, alveolar hypoventilation (AH) is rarely accompanied with ventilation-perfusion ratio heterogeneity, and, therefore, oximetry may be less sensitive for detecting AH than in patients wi...

The purpose of this work was to apply a simple method for acquisition of power output (PO) during the Wingate Anaerobic Test (WAnT) at a high sampling rate ( S(R)) and to compare the effect of lower S(R) on the measurements extracted from the PO. 26 male subjects underwent 2 WAnTs on a cycle ergometer. The reference PO was calculated at 30 Hz as a function of the linear velocity, the moment of ...

BACKGROUND Ketoprofen is a non-steroidal anti-inflammatory drug which has been widely used for domestic animals. Orally administered racemic ketoprofen has been reported to be absorbed well in pigs, and bioavailability was almost complete. The objectives of this study were to analyze R- and S-ketoprofen concentrations in plasma after oral (PO) and intra muscular (IM) routes of administration, a...