Edgar Allan Poe was one of the most celebrated writers of all time. He published several masterpieces, some of which include references to neurological diseases. Poe suffered from recurrent depression, suggesting a bipolar disorder, as well as alcohol and drug abuse, which in fact led to his death from complications related to alcoholism. Various hypotheses were put forward, including Wernicke'...

OBJECTIVE To assess the association of hypoglycemic treatment regimens with cardiovascular adverse events and mortality in a large population of type 2 diabetic patients at increased cardiovascular risk. RESEARCH DESIGN AND METHODS This analysis included 8,192 overweight patients with type 2 diabetes from the Sibutramine Cardiovascular Outcomes (SCOUT) trial randomized to lifestyle interventi...

CONTEXT Adverse drug events (ADEs) are a significant and costly cause of injury during hospitalization. OBJECTIVES To evaluate the efficacy of 2 interventions for preventing nonintercepted serious medication errors, defined as those that either resulted in or had potential to result in an ADE and were not intercepted before reaching the patient. DESIGN Before-after comparison between phase ...

We have prepared a viscous bicontinuous microemulsion consisting of water / [20 wt% POE-GIS + 30 wt% PEPTME + 47.5 wt% POE/POP-PDMS + 2.5 wt% OA)] / DMPS system. A pseudoternary phase diagram was constructed for the mixture, and the bicontinuous microemulsion phase was characterized by means of rheometry and freeze-fracture transmission electron microscopy (FF-TEM).

Application ofHFC refrigerants for air conditioners and refrigerators has been studied. Development of a common oil, based on a combination ofpolyolester and additive packages, is aimed for R-22 and HFCs refrigerants, and the evaluation tests of reliability in compressor and refrigeration system brought about good results. This refrigeration lubricant is already partly commercialized in HFC ref...

in the present paper, we consider biflatness of certain classes of semigroupalgebras. indeed, we give a necessary condition for a band semigroup algebra to bebiflat and show that this condition is not sufficient. also, for a certain class of inversesemigroups s, we show that the biflatness of ell^{1}(s)^{primeprime} is equivalent to the biprojectivity of ell^{1}(s).

PURPOSE Cortico-amygdalohippocampectomy (CAH) has become an important treatment option for patients with refractory temporal lobe epilepsy and mesial temporal sclerosis (TLE-MTS); it has resulted in a 60-70% seizure remission rate and significant quality of life (QOL) improvements. Video-electroencephalography (VEEG) monitoring has been widely used in epilepsy centers for pre-surgical evaluatio...

PURPOSE Oral leukoplakia is a well-recognized precancerous lesion of squamous cell carcinoma. When accompanied with abnormal p53 expression, it suffered a higher risk of canceration. The present study was carried out to test whether the recombinant human adenovirus-p53 could introduce wild-type p53 gene to oral leukoplakia cells and induce cell cycle arrest and apoptosis. EXPERIMENTAL DESIGN ...