CONTEXT Recently, two patients with primary ovarian insufficiency (POI) delivered healthy babies after in vitro activation (IVA) treatment followed by auto-transplantation of frozen-thawed ovarian tissues. OBJECTIVE This study sought to report the first case of live birth after IVA treatment following fresh ovarian tissue grafting in patients with POI, together with monitoring of follicle dev...

Studies were conducted in conscious 42-h-fasted dogs to determine how much of insulin's effect on hepatic glucose uptake arises from its direct hepatic action versus its indirect (extrahepatic) action. Each experiment consisted of equilibration, basal, and experimental periods. During the latter, somatostatin, basal intraportal glucagon, portal glucose (21.3 micromol x kg(-1) x min(-1)), and pe...

Stabilization of mast cell (MC) degranulation has been proposed to prevent postoperative ileus (POI). Nerve growth factor (NGF) mediates MC degranulation. The aim of the study was to evaluate whether NGF receptor antagonist K252a acts as a MC stabilizer in vitro and in vivo model of POI. Peritoneal mast cells (PMCs) were obtained from Sprague-Dawley rats and were incubated with K252a and expose...

Postoperative ileus (POI) after open abdominal surgery and bowel resection can lead to significant patient discomfort, morbidity, and prolonged length of stay in the hospital. Several factors have been implicated in the pathophysiology of POI, including surgical manipulation of the bowel, inflammation, inhibitory neural reflexes, and endogenous and exogenous opioids. Alvimopan (Entereg), approv...

Digital cities of the future should provide digital information about points-of-interest (POIs) for virtually any user context. Starting from several Google Fusion tables about city POIs, we extracted and transferred useful POI data to RDF to be accessible by SPARQL requests. In this initial application context, we concentrated on museum and restaurant resources as the result of a precision-ori...

Recommendation systems aim to recommend items or packages of items that are likely to be of interest to users. Previous work on recommendation systems has mostly focused on recommending points of interest (POI), to identify and suggest top-k items or packages that meet selection criteria and satisfy compatibility constraints on items in a package, prior work, this paper investigates two issues ...

Topica is an application that enriches the Social Web with semantic data, to enable collective perception of Points of Interest (POIs), which are human constructs that describe information about locations (e.g., restaurants, attractions, cities). Topica provides an extra layer of information, compared to existing applications for browsing POIs, by modelling hidden characteristics of POIs, by: (...

The rapidly growing of Location-based Social Networks (LBSNs) provides a vast amount of check-in data, which enables many services, e.g., point-ofinterest (POI) recommendation. In this paper, we study the next new POI recommendation problem in which new POIs with respect to users’ current location are to be recommended. The challenge lies in the difficulty in precisely learning users’ sequentia...

Travel itinerary recommendation is an important but challenging problem, due to the need to recommend captivating Places-of-Interest (POI) and construct these POIs as a connected itinerary. Another challenge is to personalize these recommended itineraries based on tourist interests and their preferences for starting/ending POIs and time/distance budgets. Our work aims to address these challenge...

Coltheart and Rastle (1994) and Rastle and Coltheart (1999) observe that their Dual Route Cascaded (DRC) model of single-word reading has a left -to-right grapheme-tophoneme correspondence mechanism, distinguishing it from connectionist models of word naming which possess no such serial mechanism. In the DRC an irregular grapheme to phoneme correspondence near the beginning of a word (e.g. chef...