The mucoadhesive hydrogel film was prepared and optimized for the purpose of local drug delivery to oral cavity for the treatment of oral Candidiasis. The mucoadhesive hydrogel film was prepared with the poly(vinyl alcohol) by freeze/thaw crosslinking technique. 3(2) full factorial design was employed to optimize the formulation. Number of freeze/thaw cycles (4, 6, and 8 cycles) and the concent...

A selectively cross-linking method, which is based on the ‘‘di–diol” interaction between poly(vinyl alcohol) and borate and the strong electrostatic interaction between chitosan and tripolyphosphate, was developed. Chitosan/poly(vinyl alcohol) films cross-linked separately with borate, tripolyphosphate and borate/tripolyphosphate were then prepared in terms of this method. Water vapor permeatio...

A water-induced self-healing polymer hybrid was prepared by the hybridization of poly(vinyl alcohol) with smectite clay in aqueous media and subsequent casting.

Graphene oxide/poly(vinyl alcohol) (GO/PVA) composite hydrogel was prepared and utilized for selective drug release at physiological pH.

We develop coarse-grained force fields for poly (vinyl alcohol) and poly (acrylic acid) oligomers. In both cases, one monomer is mapped onto a coarsegrained bead. The new force fields are designed to match structural properties such as radial distribution functions of various kinds derived by atomistic simulations of these polymers. The mapping is therefore constructed in a way to take into acc...

Upcycling of plastic waste is approached by designing multifunctional molecules for reactive compatibilization investigations a model polymer blend, here polyethylene (PE) and poly(ethylene- co -vinyl alcohol) (EVOH).

The present review aims to give a closer look of hydrogels based on chitosan and poly (vinyl alcohol) and to discuss their potential biomedical applications in drug delivery system. Various investigations based on chitosan/poly (vinyl alcohol) carried out recently by researchers have been reported in this review. Moreover different chemical and physical crosslinking methods used for hydrogels f...

Poly(vinyl alcohol) hydrogels have a significant range of mechanical properties based on compositional and processing parameters. Biodegradable hydrogels based on Poly(vinyl alcohol) were prepared for controlled drug delivery of bovine serum albumin. These hydrogels were synthesized by a crosslinking technique using glutaraldehyde as a crosslinker. Hydrogels containing drug were prepared by dir...

Mucoadhesive buccal patch of Aceclofenac were prepared using polymer like Gelatin, Poly Sodium CMC and Poly Vinyl Alcohol. Eight formulations were prepared with varying the concentration of Poly Sodium CMC and evaluated for various parameters like weight variation, patch thickness, volume entrapment efficiency %, and measurement of % elongation at break, folding endurance, in vitro mucoadhesive...