Background. We previously found that expression of SET gene was up-regulated in polycystic ovaries by using microarray. It suggested that SET may be an attractive candidate regulator involved in the pathophysiology of polycystic ovary syndrome (PCOS). In this study, expression and cellular localization of SET protein were investigated in human polycystic and normal ovaries. Method. Ovarian tiss...

Background: To estimate the prevalence of polycystic ovarian syndrome (PCOS) in Chinese women comprehensively and to provide references prevent PCOS.

OBJECTIVE To compare the effects of laparoscopic ovarian drilling in treating infertile polycystic ovarian syndrome in patients with and without metabolic syndrome. DESIGN Retrospective review. SETTING A university-affiliated hospital in Hong Kong. PATIENTS A total of 89 infertile anovulatory polycystic ovarian syndrome patients, who underwent laparoscopic ovarian drilling with completed ...

121 women with Polycystic Ovarian Syndrome and clomiphene citrate resistance underwent laparoscopic ovarian cautery, 63 patients were type I or typical PCOS with ovarian volume >8mL and 58 patients were type II PCOS with ovarian volume O.05). It therefore appears that the result of laparoscopic ovarian cauterization does not depend on ovary size in clomphene citrate resistant patients with...

Polycystic ovarian disease in adolescents is not uncommon. Usually underlying ovarian tumours can cause hirsutism and ovulation. A 15-year-old girl presented with infrequent cycles and hirsutism. Her baseline evaluation ruled out ovarian tumour and other endocrinological problems. She was treated with insulin sensitizers and hormone treatment. After more than a year of treatment she developed a...

In 1935 Stein and Leventhal described seven hirsute and infertile women with amenorrhoea or oligomenorrhoea in whom bilateral cystic ovarian enlargement was found at laparotomy' and thereby gave their names to a polycystic ovarian disorder. Since then, however, the protean manner of clinical presentation and the variability of biochemical changes in patients with this condition have led some pe...

BACKGROUND AND OBJECTIVES Primary hypothyroidism may be associated with ovarian enlargement and/ or cyst formation. We evaluated the effect of thyroid hormone replacement therapy on hormonal changes, ovarian volume and sonographic appearance. DESIGN AND SETTING Open, prospective study of women admitted to university gynecology clinic. PATIENTS AND METHODS The study included 26 patients with...

introduction primary amenorrhea isa condition in which a young woman has not started her menstrual periods by the age of 16-18. the principal features of polycystic ovarian syndrome (pcos) are anovulation, resulting in irregular menstruation, amenorrhea, and ovulation-related infertility. case presentation from january 2007 to june 2013 we conducted 2215 laparoscopies, out of which 605(27.6%) w...

background: endometrial integrin expression changes might be a reason for implantation failure in polycystic ovarian syndromes (pcos). objective: assessment of integrin genes and proteins expression upon endometrium in the pcos experimental mouse model was the main goal of this study. materials and methods: 30 nmri female mice were equally divided into control, experimental (pcos; received estr...

background: it is reasonable to think that some biochemical characteristics of follicular fluid (ff) surrounding the oocyte may play a critical role in determining the quality of oocyte and the subsequent potential needed to achieve fertilization and embryo development. objective: this study was carried out to evaluate the levels of ff homocysteine (hcy) in ivf candidate polycystic ovary syndro...