Mucoadhesive durg delivery systems are among novel drug delivery systems that due to their ability to adhere and remain on the mucosal surfaces and a show and sustained release of their drug contect have attracted special attention in recent years.the aim of this study was to evaluate the effect of four different important factors on the  mucoadhesive strength of a few  mucoadhesive polymers.am...

Polymeric nanoparticles (PNPs) are a group of nanocarriers employed in wide range applications. Characterization is fundamental step PNPs formulation and many basic techniques available to provide chemical-physical information such as dimensions, surface potential, stability solubility. Recently, these have been implemented with more innovative ones obtain precise knowledge the nanomaterials. I...

Hydrogel nanoparticles—also referred to as polymeric nanogels or macromolecular micelles—are emerging as promising drug carriers for therapeutic applications. These nanostructures hold versatility and properties suitable for the delivery of bioactive molecules, namely of biopharmaceuticals. This article reviews the latest developments in the use of self-assembled polymeric nanogels for drug del...

Ocular drug delivery is a very challenging area for ophthalmologists and scientists due to the structural barrier complexity of eye. Barriers such as different layers cornea, sclera, conjunctival blood flow, tear dilution limit efficacy anterior part eye in addition more barriers present posterior part. Due these, have designed studied various systems increase treatment Among conventional ocula...

Polymeric nanoparticles can prove beneficial in oncology as they sidestep limitations associated with traditional small-molecule pharmaceuticals. With respect to drug delivery, polymeric possess structural features that make them suitable...

Since last three decades delivery of the desired drug as muocoadhesive drug delivery systems has been subject of interest. Mucoadhesion involving a polymeric drug delivery system is a complex phenomenon that includes theory of diffusion, wetting, adsorption, fracture and interpenetration of polymer chains amongst various other processes. Various polymer-based properties such as the degree of cr...

Oral administration remains the most convenient way of delivering drugs. Recent advances in biotechnology have produced highly potent new molecules such as peptides, proteins and nucleic acids. Due to their sensitivity to chemical and enzymatic hydrolysis as well as a poor cellular uptake, their oral bioavailability remains very low. Despite sophisticated new delivery systems, the development o...

The combination of liposomes with polymeric scaffolds could revolutionize the current state of drug delivery technology. Although liposomes have been extensively studied as a promising drug delivery model for bioactive compounds, there still remain major drawbacks for widespread pharmaceutical application. Two approaches for overcoming the factors related to the suboptimal efficacy of liposomes...

Polymeric micelles are nanoscale core-shell structures formed by amphiphilic (block or graft) copolymers, that can self-aggregate in an aqueous medium. PMs characterized small size, spherical shape, lower critical micellar concentration, which gave higher
 stability for over conventional surfactant micelles. The core/shell structure permits polymeric micelle to entrap poor soluble drugs an...