BACKGROUND Polyphenols have received a great deal of attention due to their biological functions. Pomegranate (Punica granatum L.) is a polyphenol-rich fruit. In the past decade, studies testing the antimicrobial activity of pomegranates almost exclusively used solvent extracts instead of fresh pomegranate juice (FPJ). The use of FPJ instead of solvent extracts would reduce toxicity issues whil...

The discovery and development of natural products with potent antioxidant, anti-inflammatory, and antiapoptotic properties have been one of the most interesting and promising approaches in the search for the treatment of many neurodegenerative diseases including ischemic stroke. Serum/glucose deprivation (SGD) has served as an excellent in vitro model for the understanding of the molecular mech...

BACKGROUND The medical application of pomegranate fruits and its peel is attracted human beings. The aim of the present study was to evaluate the in vitro α-Glucosidase inhibition, antimicrobial, antioxidant property and in vivo anti-hyperglycemic activity of Punica granatum (pomegranate) fruit peel extract using Caenorhabditis elegans. METHODS Various invitro antioxidant activity of fruit pe...

Radiation therapy has been used in cancer treatment for many decades; although effective in killing tumor cells, ROS produced in radiotherapy threaten the integrity and survival of surrounding normal cells. Recent studies have indicated that some commonly used medicinal plants may be good sources of potent but non-toxic radioprotectors. The pomegranate, Punica granatum L., an ancient, mystical,...

milk and fruit juice due to the high nutritional value, are widely consumed by society’s people. pomegranate juice in spite of nutritional value has oldness in consumption and milk-pomegranate juice product could be desirable specifically for the consumers who are keen to experience new formulation and taste. milk-juice beverage is a type of acidified milk drink that one of the main problems in...

ABSTRACT - Vermicomposting with pomegranate pulp can not only prevent pollution of the environment but can also create jobs, generate added value and prevent the waste of energy and the country's capital. This factorial experiment was conducted in a completely randomized design. The first factor (a) in two levels contained neutralized pomegranate pulp with lime and non-neutralized pulp. The sec...

This study was carried out to determine the effects of supplementing different levels (0, 0.5 and 1% of buffered rumen fluid) of methanolic extract of pomegranate peel, on rumen fermentation kinetics of four oil seed meals (soybean meal, cotton seed meal, rapeseed meal and sunflower seed meal), using in vitro gas production technique. The samples were incubated in syringes containing rumen liqu...

The carob moth, Ectomyelois ceratoniae (Zeller 1839) (Lepidoptera: Pyralidae) is the most important pest of pomegranate, Punica granatum L. (Myrtales: Ponicaceae), in Iran. In this study, 6 amplified fragment length polymorphism primer combinations were used to survey the genetic structure of the geographic and putative host-associated populations of this pest in Iran. An AMOVA was performed on...

PURPOSE Phytochemicals in plants may have cancer preventive benefits through antioxidation and via gene-nutrient interactions. We sought to determine the effects of pomegranate juice (a major source of antioxidants) consumption on prostate-specific antigen (PSA) progression in men with a rising PSA following primary therapy. EXPERIMENTAL DESIGN A phase II, Simon two-stage clinical trial for m...

BACKGROUND Co-products obtained from pomegranate juice processing contain high levels of polyphenols with potential high added values. From value-addition viewpoint, the aim of this study was to evaluate the stability of polyphenolic concentrations in pomegranate fruit co-products in different solvent extracts and assess the effect on the total antioxidant capacity using the FRAP, DPPH˙ and ABT...