Cross-docking is a new warehousing policy in logistics which is widely used all over the world and attracts many researchers attention to study about in last decade. In the literature, economic aspects has been often studied, while one of the most significant factors for being successful in the competitive global market is improving quality of customer servicing and focusing on customer satisfa...

Hsp90 is a major protein involved in the stabilization of various proteins in cancer cells. The present investigation focused on the molecular docking simulation studies of flavanols as inhibitors of Hsp90 at the high affinity adenosine triphosphate (ATP) binding site and analyzed absorption, distribution, metabolism, excretion and toxicity (ADME-toxicity). The molecular docking analysis reveal...

This paper aims to model a consumer goods cross-docking problem, which is solved using metaheuristics minimize makespan and determine the capacity in terms of inbound outbound docks. The consumer-goods problem represented through docks, customer orders (products be delivered customers), as solution method. Simulated annealing (SA) particle swarm optimization (PSO) are implemented solve problem....

The yeast transport GTPase Ypt6p is dispensable for cell growth and secretion, but its lack results in temperature sensitivity and missorting of vacuolar carboxypeptidase Y. We previously identified four yeast genes (SYS1, 2, 3, and 5) that on high expression suppressed these phenotypic alterations. SYS3 encodes a 105-kDa protein with a predicted high alpha-helical content. It is related to a v...

Autodock and its various variants are widely utilized docking approaches, which adopt optimization methods as search algorithms for flexible ligand virtual screening. However, many of them have their limitations, such poor accuracy dockings with highly ligands low efficiency. In this paper, a multi-swarm algorithm integrated environment is proposed to design high-performance high-efficiency pro...

In order to reduce costs and increase efficiency of a supply chain system, cross docking is one of the most important strategies of warehousing for consolidation shipments from different suppliers to different customers. Products are collected from suppliers by inbound trucks and then moved to customers by outbound trucks through cross dock. Scheduling of trucks plays important role in the cros...

Human papillomaviruses (HPV) are a group of strong human carcinogen viruses considered to be the fourth leading cause of mortality among women in the world. HPV is the most important cause of cervical cancer, which is the second most common cancer in women living in low and middle-income countries. To date, there is no effective cure for an ongoing HPV infection; therefore, it is required to in...