introduction: colonoscopy is an invasive method that is painful for patient especially for children. the objective of this research was investigation of the effect of supermint oral drop (peppermint essence) on the patient and colonoscopist group satisfaction during colonoscopy.    materials and methods: one hundred and one patient's candidate for colonoscopy was randomly divided into two ...

introduction: few studies are conducted on the efficacy of antispasmodics in the treatment of functional gastrointestinal disorders in children. we evaluated the effectiveness of a smooth-muscle relaxant (mebeverine) in the treatment of childhood functional abdominal pain (fap).   materials and methods: children (n=115, aged 6-18 years) with fap were randomized to receive mebeverine 135 mg twic...

introduction: complications of caustic ingestion swallowing in children of singe to gullet severe  stricture and andoscopic actions and multiple surgeries is different that increase the risk of gastrointestinal perforation and gastrointestinal malignancies ..... because acid substances have  bad taste and these are tissue coalescence in location of contact thus attribute alkali make lose of inj...

introduction: acute lymphoblastic leukemia (all) and non-hodgkin's lymphoma (nhl) are the most common childhood and adolescence malignancy respectively.due to the increasing survival of these children, today late side effects of treatments are important. therapies such as corticosteroids, cytotoxic and radiotherapy effect on bone density and put the child at risk of osteoporosis and pathol...

introduction: limited data are available on the effectiveness of antidepressants in the treatment of functional gastrointestinal disorders in children. we evaluated the effectiveness of citalopram in the treatment of childhood functional abdominal pain (fap).   material and methods: children with fap (n=115, aged 6-18 years) received either citalopram 20 mg/day or placebo for 4 weeks. treatment...

background and objective: asthma is the most common chronic disease of childhood. the disease is caused by a temporary blockage of airflow due to chronic inflammation of the airways . one of the conditions that often occur with asthma and exacerbate disease, is gastroesophageal reflux. the aim of this study is to evaluate the role of acid suppressing therapy in patients with refractory asthma. ...

introduction: antibiotic- associated diarrhea is a common problem in pediatric population. there is growing interest in probiotics, probiotics and synbiotics for prevention of this complication because of their worldwide availability as dietary supplements. the aim of this study was to assess the efficacy of a synbiotic mixture in prevention of antibiotic- associated diarrhea.   materials and m...

Background: Pancreatic islet transplantation has emerged as a promising treatment for type I diabetes. However, its efficacy is severely hampered due to poor islet engraftment and revascularization, which have been resulted to partially loss of transplanted islets. It has been shown that local delivery of vascular endothelial growth factor (VEGF) could accelerate transplanted islet revasculari...