Chemical weathering and the subsequent export of carbonate alkalinity (HCO3- + CO3-2) from soils to rivers account for significant amounts of terrestrially sequestered atmospheric CO2. We show here that during the past half-century, the export of this alkalinity has increased dramatically from North America's largest river, the Mississippi. This increased export is in part the result of increas...

In previous work, we used a permeabilized cell assay that reconstitutes nuclear export of protein kinase inhibitor (PKI) to show that cytosol contains an export activity that is distinct from Crm1 (Holaska, J.M., and B.M. Paschal. 1995. Proc. Natl. Acad. Sci. USA. 95: 14739-14744). Here, we describe the purification and characterization of the activity as calreticulin (CRT), a protein previousl...

The eukaryotic translation initiation factor 4E (eIF4E) controls gene expression through its effects on mRNA export and cap-dependent translation, both of which contribute to its oncogenic potential. In contrast to its translation function, the mRNA export function of eIF4E is poorly understood. Using an RNP isolation/mass spectrometry approach, we identified candidate cofactors of eIF4E mRNA e...

Los1p, the Saccharomyces cerevisiae exportin-t homologue, binds tRNA and functions in pre-tRNA splicing and export of mature tRNA from the nucleus to the cytosol. Because LOS1 is unessential in yeast, other pathways for tRNA nuclear export must exist. We report that Cca1p, which adds nucleotides C, C, and A to the 3' end of tRNAs, is a multicopy suppressor of the defect in tRNA nuclear export c...

The aim of this study is to define and introduce the variable of export entrepreneurship and factors affecting it in a global export-centric model. However, we seek to find the effect of the variables of export entrepreneurship and export market orientation‎ on export performance. To test the research hypotheses, a sample of 296 people employed in food and agricultural products company located ...

Private standards are increasingly governing international food trade, but little is known about the implications for developing countries. The objective of the study is to provide evidence in the ongoing debate on standards as barrier or catalyst for developing countries’ export. We use the Peruvian fresh asparagus export sector as a case study and provide empirical panel data evidence on the ...

Hyaluronan is synthesized within the cytoplasm and exported into the extracellular matrix through the cell membrane of fibroblasts by the MRP5 transporter. In order to meet the law of electroneutrality, a cation is required to neutralize the emerging negative hyaluronan charges. As we previously observed an inhibiting of hyaluronan export by inhibitors of K(+) channels, hyaluronan export was no...