Staphylococcus aureus has long been recognized as a major cause of hospital-acquired infection. Over the last decade, methicillin-resistant S. aureus (MRSA) strains have become endemic in hospitals worldwide, including in the UK. Accordingly, the frequency of MRSA isolation has increased dramatically. Glycopeptides, such as vancomycin, are often the therapeutic drugs of choice for serious MRSA ...

Before the emergence of penicillin-resistant pneumococci, penicillin was usually the first-line antibiotic in the treatment of pneumococcal infections. The global increase of resistant pneumococci has jeopardized the treatment of pneumococcal infections. Additional resistance to cephalosporins has further limited the treatment options against penicillin-resistant isolates. Furthermore, pneumoco...

Co-amoxiclav is widely used in France to treat different infectious diseases, in particular community-acquired otitis, sinusitis and pneumonia, and occasionally urinary tract infections (UTIs). While the mechanisms of resistance to co-amoxiclav have been well defined, particularly in Escherchia coli, the influence of co-amoxiclav treatment on the in vivo selection of E. coli resistant to co-amo...

Extended-spectrum -lactamases (ESBLs), such as the plasmid-mediated class A TEMand SHV-type enzymes, have developed by stepwise mutations in their structural genes, resulting in either single or multiple amino acid changes in the encoded enzymes, and these changes sufficiently remodel the active site to allow attack on aminothiazolyl compounds. Since they were first identified at the beginning ...

For several decades there has been a steady increase in the incidence of bacterial infections caused by Gram-positive bacteria. Gram-positive infections have become a serious problem, especially in the nosocomial setting, and the treatment of these infections is complicated by the emergence of multidrug-resistant pathogens. Staphylococci are among the most frequent causes of both communityand h...

Two parameters are commonly used for the evaluation of antibiotic efficacy in animal models: bacterial counts in tissue fluids and survival rate. The second parameter is easy to assess and seems more relevant from the clinical perspective; a curative dose is used as a reliable end-point for showing subtle differences in antibiotic behaviour. Reduction in bacterial counts provides information on...

Antibiotic Resistance Monitoring & Reference Laboratory, Central Public Health Laboratory, 61 Colindale Avenue, London NW9 5HT, UK; Université Libre de Bruxelles, Hôpital Erasme, Route de Lennik 808, Bruxelles 1070, Belgium; Hospital Geral Santo Antonio, Serviço Microbiologia, Largo Pr. Abel Salazar, Oporto 4099-00, Portugal; Hospital Ramon y Cajal, Servicio de Microbiologia, Carretera De Colme...

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AMA Budna P, Szablewska A. The role of the midwife in puerperium care women with HELLP syndrome, considering impact disease on mother-child relationship. Nursing Problems / Problemy Pielęgniarstwa. 2023;31(1):49-53. doi:10.5114/ppiel.2023.129139. APA Budna, P., & Szablewska, (2023). Pielęgniarstwa, 31(1), 49-53. https://doi.org/10.5114/ppiel.2023.129139 Chicago Paulina, and Anna W. Szablewska. ...

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Seema S, Manju M. EMOTIONAL INTELLIGENCE AND PERSONALITY AS CORRELATES OF THE PSYCHOLOGICAL WELL-BEING ADOLESCENTS: A CROSS-SECTIONAL STUDY IN NORTH INDIA. Health Problems of Civilization. 2023;17(1):49-61. doi:10.5114/hpc.2023.125113. APA Seema, S., & Manju, (2023). Civilization, 17(1), 49-61. https://doi.org/10....