OBJECTIVES To determine the frequency of pepsin detection in tracheal aspirate (TA) samples of mechanically ventilated premature neonates and its association with feedings and methylxanthine therapy. PATIENTS AND METHODS Serial TA samples (days 1, 3, 5, 7, 14, 21, 28 and >28 days) were collected from premature neonates receiving ventilatory support. An enzymatic assay with a fluorescent subst...

  Background :Severe neonatal hyperbilirubinemia is associated with significant morbidity and mortality. This study was conducted to investigate the causes of severe hyperbilirubinemia leading to Exchange Transfusion (ET) from March 2009 to March 2011 in Bahrami children hospital, Tehran, Iran in order to establish guidelines to prevent profound jaundice & ET.   Methods : 94 neonates underwent ...

Persistent patency of the ductus arteriosus is a major cause of morbidity and mortality in premature infants. In infants born prior to 28 weeks of gestation, a haemodynamically significant patent ductus arteriosus (PDA) can cause cardiovascular instability, exacerbate respiratory distress syndrome, prolong the need for assisted ventilation and increase the risk of bronchopulmonary dysplasia, in...

introduction: one of the most important criteria for health is neonatal mortality. mortality in neonatal period is high, that is about 65% of mortality in infancy occurs below the age of one year. this study was conducted to determine mortality rate in neonates in motazedi hospital of kermanshah during 2002 to 2003. materials & methods: this descriptive study was conducted on the dead neonates ...

To assess maturation of central serotonin and catecholamine pathways at birth, we measured lumbar CSF homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA), stable acid metabolites of dopamine and serotonin, using HPLC with electrochemical detection. CSFs from 57 neonates (38 premature and 19 at term) and 13 infants 1-6 months old were studied. HVA levels increased with maturity (p le...

Endotracheal intubation is a common daily procedure used for sustaining life in premature and term neonates in the neonatal intensive care unit. This procedure can be associated with some iatrogenic complications. One of these complications is ingesting a laryngoscope light bulb, and it is an extremely rare complication in neonates. The consequences of ingestion or aspiration may be serious and...

Introduction: Improvements in newborn intensive care led to decreased mortality, but increased the morbidity rates of preterm infants. This study have designed to evaluate the short- term outcome in premature infants admitted to NICU at Amirkola Children Hospital(ACH) , northern Iran from Mar20,2010- Mar21,2011 Methods: All the premature infants admitted to NICU and newborn services from Mar20...

The diagnosis of intussusception in neonates is difficult. It is less frequent than the other neonatal abdominal issues (Less than 1.3% of all cases of intussusception occur in term neonates). The clinical feautures show great similarities with necrotizing enterocolitis (NEC). Nevertheless this disease remains exceedingly rare in premature neonates. The intussusception is frequently located in ...

Central venous catheters are widely used in children, particularly in very-low-birth-weight infants in whom long-term access to the venous system is required. This may be achieved by using peripherally inserted central catheters or tunnelled central venous lines (eg Broviac or Hickman lines). Previous case reports of fractured central catheters in premature neonates have involved peripherally i...

12 McLaws ML, Pantle AC, Fitzpatrick KR, Hughes CF. More than hand hygiene is needed to affect methicillin-resistant Staphylococcus aureus clinical indicator rates: Clean hands save lives, part IV. Med J Aust 2009;191 (8 Suppl):S26–S31. 13 Jain R, Kralovic SM, Evans ME, Ambrose M, Simbartl LA, Obrosky DS, et al. Veterans Affairs initiative to prevent methicillin-resistant Staphylococcus aureus ...