midst of the ongoing debate on the extent and therapeutic value of lymphadenectomy in endometrial cancer. Several groups have recognized that preoperative and intraopera-tive identification of low risk patient groups may allow the omission of lymphadenectomy thereby averting unnecessary morbidity and reducing costs while potentially achieving favorable oncologic outcomes [1-9]. Although the rol...

BACKGROUND It has been suggested that the routine use of statins preoperatively would reduce the risk of postoperative infection. We conducted this study to explore whether preoperative statin use was associated with infection after cardiac surgery (recipients of which have a higher-than-average risk of postoperative infection). METHODS We performed secondary analysis of data collected in a p...

IMPORTANCE Postoperative hospital-acquired infections (HAIs) may result from disruption of natural barrier sites. Recent studies have linked vitamin D status and barrier site integrity. OBJECTIVE To investigate the association between preoperative vitamin D status and the risk for HAIs. DESIGN, SETTING, AND PARTICIPANTS A retrospective analysis was performed using propensity score methods t...

With the universal adoption of antibiotic prophylaxis prior to prostate biopsy, the current risk of post-biopsy infection (including sepsis) is <2%. Preoperative prophylactic antibiotic regimens can vary, and although fluoroquinolones have emerged as the standard of care, there is no universally agreed upon preoperative antibiotic regimen. Recently, an increase in the proportion of postoperativ...

BACKGROUND Postoperative delirium is associated with increased morbidity and mortality. Preexisting cognitive impairment and depression have been frequently cited as important risk factors for this complication. This prospective cohort study was designed to determine whether individuals who perform poorly on preoperative cognitive tests and/or exhibited depressive symptoms would be at high risk...

INTRODUCTION Acute renal failure (ARF) following cardiothoracic surgery (CTS) is a major complication that increases postoperative morbidity and mortality. Recognizing patients at risk for ARF may lead to modified operative techniques, preoperative drug choice, or improved informed consent. The study objective was to identify and confirm preoperative and intraoperative risk factors for ARF foll...

BACKGROUND Previous studies have reported that pretreatment thrombocytosis is associated with poor outcomes in several cancer types. This study was designed to evaluate the prognostic significance of preoperative thrombocytosis in patients with non-small cell lung cancer (NSCLC) who undergo surgery. METHODS We retrospectively reviewed the records of 199 patients who underwent R0 resection for...

AIM To evaluate the clinical and prognostic significance of preoperative and postoperative cytokeratin 19 (CK19) and carcinoembryonic antigen (CEA) mRNA levels in peripheral blood of patients with gastric cardia cancer (GCC). METHODS We detected the preoperative and postoperative mRNA levels of CK19 and CEA in peripheral blood of 129 GCC patients by using reverse transcription-polymerase chai...