Epidemiology is one of the areas of medical research which by definition should have immediate clinical implications, since its inferences are based on and apply to humans and should in theory be directly transferable to clinical and preventive measures. However, interchange of information has not always been easy, and this has constituted a substantial drawback to both the epidemiologist and t...

Background South Africa has a significant violence problem. The exposure of girls and women to interpersonal violence is widespread, and the victimization of men, especially to severe and homicidal forms of aggression, is of considerable concern, with male homicide eight times the global rate. In the last two decades, there have been a plethora of South African policies to promote safety. Howev...

Adherence to oral endocrine therapy in adjuvant breast cancer settings is a substantial clinical problem. To provide current perspective on adherence to oral endocrine therapies, a comprehensive literature review was conducted. In adjuvant trials, endocrine therapy adherence is relatively high with greater adherence for aromatase inhibitors compared with tamoxifen. In contrast, adherence to adj...

Breast cancer is a burden for western societies, and an increasing one in emerging economies, because of its high incidence and enormous psychological, social, sanitary and economic costs. However, breast cancer is a preventable disease in a significant proportion. Recent developments in the armamentarium of effective drugs for breast cancer prevention (namely exemestane and anastrozole), the n...

context ebola hemorrhagic fever (ehf) is amongst severe and fatal viral hemorrhagic fevers. in february 2014, a strain of the ebola virus appeared in guinea and then in liberia, sierra leone, and mali. the aim of this study was to review the literature on ehf and discuss its routes of transmission and prevention. evidence acquisition we searched medical databases (pubmed, scopus) from july 1970...

objectives to examine the military service predictors resulting in worsening drug abuse status. patients and methods a cross-sectional study with 3140 young soldiers was conducted in summer and autumn of 2010 and; the participants completed three questionnaires, namely the texas christian university drug screen (tcuds) ii, the addiction severity index and a questionnaire designed by the researc...

ankle sprains are among the most common injuries in athletes and military recruits. high bmi, previous history of ankle sprain, poor muscle strength, proprioceptive deficits, limitation in rom and balance are important risk factors for ankle sprain. recent studies have shown that external support such as brace and tape significantly reduces the risk of primary and recurrent ankle sprains in ath...

alcohol, with its impact on both communicable and non-communicable diseases, is considered as the third global public health priority. alcohol ranked third among causes of ill health and premature death, and ranked second in terms of cost among all the substances of abuse, after tobacco, even though nearly half the world's population drinks alcohol. in most countries, where alcohol is considere...

background preeclampsia is one of the leading causes of maternal mortality and morbidity. its prevalence varies between 10-25% among high-risk pregnant patients. objectives the aim of this study was to determine whether treatment with acetylsalicylic acid (asa) reduces the incidence of preeclampsia among pregnant women with abnormal uterine artery flow. patients and methods in this double-blind...