This study compared dynamics of the germ cell population in two swine breeds that differ in prolifacy, White Composite (WC) and Meishan (MS), during fetal and neonatal life and in mature sows. Germ cell populations developed in a similar pattern in these two diverse breeds during fetal life. Maximal germ cell number was observed at 90 days postcoitum (dpc) in both WC and MS gilts, and substanti...

Background: Whenever the balance between Antioxidants and reactive oxygen species (ROS) is disrupted towards an overabundance of ROS, oxidative stress (OS) occurs. There is evidence that glutathione as an intracellular antioxidant plays an important role against ROS in female reproductive system. BSO is a selective inhibitor of glutathione peroxidas. The aim of the present study is to investiga...

The first critical transition in follicular development, the activation of primordial follicles to leave the pool of resting follicles and begin growth, is poorly understood, but it appears that the balance between inhibitory and stimulatory factors is important in regulating the exodus of follicles from the resting pool. There is evidence that anti-Mullerian hormone (AMH; also known as MIS) in...

introduction: genital system is important herd in animal's creation. it is necessary for animal reproduction. mammal has two sex in genital system such as male and female in separated animals. animal reproduction destroyed by disorder of genital system. in this case, animals cannot produce an animal similar to them. finally it cause overthrow a species of animals. methods: histomorphologic...

In mammalian ovaries, a fixed population of primordial follicles forms during the perinatal stage and the oocytes contained within are arrested at the dictyate stage of meiotic prophase I. In the current study, we provide evidence that the level of cyclic AMP (cAMP) in oocytes regulates oocyte meiotic prophase I and primordial folliculogenesis in the perinatal mouse ovary. Our results show that...

Mobilization of endogenous retrotransposons can destabilize the genome, an imminent danger during epigenetic reprogramming of cells in the germline. The P-element-induced wimpy testis (PIWI)-interacting RNA (piRNA) pathway is known to silence retrotransposons in the mouse testes. Several piRNA pathway components localize to the unique, germline structure known as the nuage. In this study, we su...

Oogenesis in fetal pig ovaries comprises the successive changes from the primordial germ cells to the dictyotene oocytes in primordial ovarian follicles. In this study the observations were carried out with an electron microscope and stereological analysis was performed. At the ultrastructural level there are no differences between the primordial germ cells and oogonia, but oogonia are connecte...

The creation of the pool of follicles available for selection and ovulation is a multi-faceted, tightly regulated process that spans the period from embryonic development through to the first reproductive cycle of the organism. In mice, this development can occur in mere weeks, but in humans, it is sustained for years. Embryonic germ cell development involves the migration of primordial germs c...

Retinoic acid is like a steroid hormone that plays a role in embryo formation, proliferation of spermatogonia cells, ephitelial cells differentiation and organogenesis. Retinoic acid can influences seminiferous tubule formation during embryonic testis development and also play a role in the regulation of ovarian function and female reproductive tract by suppressing the hormones FSH receptor exp...

In mammals, following implantation of the embryo, a small number of cells from the epiblast eventually become the precursors of primordial germ cells (reviewed by Edson et al., 2009). After mitotic proliferation of the primordial germ cells, migration to the genital ridges and rapid proliferation again, meiosis is initiated in the oogonia at about day 13 of development in mice, at day 82 in bov...