Biomarkers that facilitate the prediction of breast cancer prognosis can improve the quality of life in patients during the long period of illness and treatment. Particularly in recent years, with the advent of a more exhaustive analysis of genetic information and gene products, the molecular mechanisms at play during breast cancer have gradually become clearer. In the present study, a systemat...

OBJECTIVE Socioeconomic and cultural factors influence breast cancer prognosis. The effect of these factors on breast cancer was evaluated among women who live in Gaziantep and its surroundings. MATERIALS AND METHODS female patients who were admitted to Gaziantep University Oncology Hospital with a diagnosis of breast cancer between October 2006-July 2013 were included in the study. The effec...

Gene expression signatures are commonly used to create cancer prognosis and diagnosis methods, yet only a small number of them are successfully deployed in the clinic since many fail to replicate performance on subsequent validation. A primary reason for this lack of reproducibility is the fact that these signatures attempt to model the highly variable and unstable genomic behavior of cancer. O...

INTRODUCTION Several studies evaluated the relation between colorectal cancer prognosis and various factors such as: depth of tumor invasion, involved lymph nodes size, counts and locations, metastatic nest expansion. We assessed the prognostic significance of the ratio between metastatic nest and involved lymph node diameter in colorectal cancer cases. METHODS A historical cohort study was c...

Previous studies have suggested that mitochondrial DNA (mtDNA) copy number was associated with cancer risk. However, no solid conclusion revealed the potential predictive value of mtDNA copy number for cancer prognosis. The present meta-analysis was performed to clarify the problem. Hence, we performed a systematic search in PubMed, EmBase, Web of Science databases independently and a total of ...

background: hyponatremia has poor outcomes in other cardiopulmonary disorders, but its predictive value in predicting mortality of patients with acute pulmonary embolism is unknown. so, we evaluate the mortality of inpatients diagnosed with pulmonary embolism (pe) who had hyponatremia at the time of admission. materials and methods: by conducting a cohort study in patients with acute pulmonary ...

the aim of this study was to determine the prognosis and survival for patients with borderlineovarian tumor (bot). a retrospective review of 30 patients with serous andmucinous bot treated at or referred to our institution was performed. fifteenpatients (50%) had serous, and the others had mucinous bot. about 86% of allpatients in both groups were in stage i of the disease. the recurrent diseas...

Background: Nowadays long non-coding RNAs are known as interesting functional part of the transcriptome. LncRNA SNHG6 was reported to be expressed more in breast cancer tissues than non-tumor ones. As a frequent cancer among women, breast cancer treatment needs applied biomarkers for fast prognosis and diagnosis. SNHG6 RNA and its splice variants could be considered as molecula...