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We aimed to understand the extent of the pursuit for statistically significant results in the prognostic literature of cancer. We evaluated 340 articles included in prognostic marker meta-analyses (Database 1) and 1575 articles on cancer prognostic markers published in 2005 (Database 2). For each article, we examined whether the abstract reported any statistically significant prognostic effect ...

in this article, we evaluated 17 iranian soldiers who were exposed to mustard gas utilized by the iraqi forces in the war fronts. their clinical symptoms and signs, laboratory tests, and other parameters were carefully assessed, an attempt was made to identify a finding of prognostic significance, and patients who recovered from the acute phase were followed to determine possible long-term effe...

Recently developed prognostic tests in early Rai and Binet stage chronic lymphocytic leukemia (CLL) require considerable technologic expertise and are not available worldwide. Smudge cells are CLL cells ruptured during smear preparation. We hypothesized that smudge cell formation is inversely correlated with expression of vimentin, a cytoskeletal protein and prognostic marker, and that the perc...

BACKGROUND Oxidative injury is an important cause of the neurologic lesion in stroke. Serum bilirubin is considered a natural antioxidant that may affect the prognosis of stroke. The purpose of this study was to evaluate the prognostic significance of bilirubin in stroke patients. METHODS A prospective cross-sectional study was conducted in Medical Units of Khyber Teaching Hospital, Peshawar....

In gynecologic oncology valid prognostic factors are necessary to estimate the course of disease and to define biologically similar subgroups for analysis of therapeutic efficacy. The presented study is a prospective study concerning prognostic significance of DNA ploidy and S-phase fraction in breast cancer following enrichment of tumor cells by cytokeratin labelling. Epithelial cells were lab...

There is currently much research devoted to the study of vascular biology in intact humans. These efforts aim to translate findings from the basic science arena to a better understanding of the pathophysiology of atherosclerosis and its complications. Markers of vascular risk have been used as surrogate end points in treatment studies. More recently, long-term studies have emerged that speak to...

UNLABELLED Extrasystoles (RVES) from the right ventricular outflow tract (RVOT) are a common arrhythmia in routine ECGs. METHODS In this prospective study 56 consecutive patients with RVES (22 males, 34 females) were examined for morphological and/or functional right ventricular (RV) abnormalities by 12-lead, Holter, exercise ECGs, transthoracic echocardiography and signal averaging. The foll...