Fragmentation of QRS (fQRS) complex is an easily evaluated non-invasive electrocardiographic parameter. Fragmentation of narrow QRS is defined as presence of an additional R wave (R') or notching in the nadir of the S wave, or the presence of > 1 R' in 2 contiguous leads, corresponding to a major coronary artery territory on the resting 12-lead ECG. Fragmentation of wide complex QRS consists of...

BACKGROUND Angiographic progression of coronary atherosclerosis is frequently observed in clinical practice and is used as an end point in clinical trials; however, its prognostic significance is unclear. METHODS AND RESULTS Progression defined as an increase in diameter stenosis by > or = 15% of at least one coronary lesion was seen in 141 (42%) of 335 patients who underwent repeat coronary ...

MircroRNA functions as a tumor suppressor or a promoter in cholangiocarcinoma (CCA). Researchers have found that miR-203 functioned as tumor suppressor in many types of cancer. However, the role of miR-203 that plays in CCA remains to be clarified. We aimed to detect the expression level and the prognostic significance of miR-203 in CCA tissues. qRT-RCR was performed to examine the miR-203 expr...

A patient with posthypoxic "alpha coma" is described whose EEGs were recorded before coma, within two hours following the onset of coma and after recovery. The differences observed between the alpha activity during coma and that seen before and after suggest that the alpha activity during coma and the physiologic alpha rhythm are different phenomena. This case, as well as others reported, also ...

SUMMARY The purpose of this study was to determine the prevalence of repetitive ventricular responses caused by non-bundle-branch re-entry and bundle-branch re-entry in 47 patients with and in 50 patients without ventricular tachycardia. We also compared the prevalence of repetitive ventricular responses using two types of electrophysiological stimulation: single premature ventri-cular stimulat...

Prognostic Significance. of Cardiac Cinefluoroscopy for Coronary Calcific Deposits in Asymptomatic Hi h Risk Subjects 19 ROBERT C. DETRANO, MD, PHD, NATHAN D. WONG, PHD, * WEIYI TANG, MD, WILLIAM J. FRENCH, MD, FACC, DEMETRIOS GEORGIOU, MD, EDDY YOUNG, MD, OLEH S. BREZDEN, MA, TERENCE M. DOHERTY, BA, KENNETH A. NARAHARA, MD, FACC, BRUCE H. BRUNDAGE, MD, FACC Torrance, Los Angeles and Irvine, Ca...

PURPOSE Macrophages are migratory cells that are frequently recruited to the site of tumors. Their presence is associated with poor clinical outcome in a variety of epithelial malignancies. The aim of this study is to examine the prognostic significance of tumor-associated macrophages in sarcomas. EXPERIMENTAL DESIGN Global gene expression profiling data of a series of soft tissue tumors were...

In this article, we evaluated 17 Iranian soldiers who were exposed to mustard gas utilized by the Iraqi forces in the war fronts. Their clinical symptoms and signs, laboratory tests, and other parameters were carefully assessed, an attempt was made to identify a finding of prognostic significance, and patients who recovered from the acute phase were followed to determine possible long-term...

OBJECTIVES To clarify clinical manifestations, association with disease activity, and prognostic impact of thrombocytopenia using simple and reliable indices. METHODS 632 patients were reviewed retrospectively. Fifty patients with thrombocytopenia were included as cases and matched with 100 control patients. Clinical manifestations at first thrombocytopenic episode were recorded. Classificati...

BACKGROUND Erythropoietin (Epo) administration has been reported to have tumor-promoting effects in anemic cancer patients. We investigated the prognostic impact of endogenous Epo in patients with pancreatic ductal adenocarcinoma (PDAC). METHODOLOGY The clinico-pathological relevance of hemoglobin (Hb, n = 150), serum Epo (sEpo, n = 87) and tissue expression of Epo/Epo receptor (EpoR, n = 104...