نتایج جستجو برای: prostate cancer
تعداد نتایج: 933099 فیلتر نتایج به سال:
Skeletal involvement is the second most common site of metastases after lymph nodal metastases in patients with prostate cancer. The skeletal metastases from prostate cancer are osteoblastic in nature and show increased tracer avidity on the bone scan. Focal tracer avid lesion in skeleton especially in skull requires the careful examination by further investigation. The patients with skull meta...
Background and Objective: Prostate cancer is reported to affect approximately 70% of men and is the second leading cause of death in men. An early diagnosis and screening can reduce the associated complications and mortality rate. Case Presentation: A 52-year-old man complaining of a backache for eight months reported to the hospital. The initial examination showed him to be suffering from an ...
Background: A series of biochemical reactions are involved in the endogenous production of estrogens. Their final and rate-limiting step is catalyzed by aromatase belonging to the class XIX of cytochrome P450. CYP19 is a key enzyme for estrogen synthesis in males. It catalyzes the irreversible conversion of androstenedione and testosterone to estrone and estradiol-17&beta, respectively. Aromata...
In regard with increasing use of brachytherapy for treatment of cancer, especially prostate cancer, dosimetry of the organs surrounding prostate is necessary. The received dose by prostate is relatively high and the healthy organs surrounding prostate are potentially at a risk of high dose too. In this paper, the doses delivered to the prostate and organs of interest were calculated by MCNP4C c...
Introduction: Defects in PTEN gene play an important role in the initiation of the prostate cancer. MAGI2 is recognized as a frame which assists in stabilizing PTEN protein and enhances its tumor suppressor function. As miR-101 down-regulates MAGI2 expression, it can indirectly cause to reduce the PTEN activity. Methods:LnCap, PC3 and DU-145 prostate cancer cell lines were studied in order to ...
According to available estimates with WHO, cancers are the sixth leading cause of global human morbidity and mortality. Prostate Cancer is fifth-ranked most lethal among various cancers, hence it warrants serious, dedicated research for improving its early detection. The employed methodologies such as prostate-specific antigen test, Gleason Score, T2 Staging lack precision accuracy in condition...
Background and Aims: Epigallocatechin-3-gallate (EGCG) is a polyphenolic compound from green tea, which its anticancer effects on many types of cancers have been confirmed, but the molecular mechanism by which EGCG induces apoptosis remains unknown. The aim of the present study was to investigate anti-proliferative properties and apoptotic signaling pathway of EGCG on PC3 human prostate cancer ...
Prostate cancer is second most common with frequent metastasis occurring to bone. We report a unique case of soft tissue and bony orbital from carcinoma prostate. The patient presented after defaulting the advised treatment. He responded well radiation therapy lesion regressed completely. Our was diagnosed have an oligo-metastatic non-compliant treatment us proptosis, which later be prostate ca...
Background and aim: The distinction between benign and malignant prostate lesions is one of the important issues in pathology. Misdiagnosis in these cases can lead to unnecessary treatments. The purpose of this study was to evaluate the diagnostic value of P504S sputum penetration in diagnosis of prostate cancer. Material and Methods: In this experimental study, 33 benign samples and 33 prosta...
A case of iris metastasis secondary to prostate cancer is reported and the clinical features of the patient are described. A 75 years old man referred with a right iris tumor , secondary glaucoma and severe anterior uveitis. He had history of multiple bone metastases due to prostate cancer. The iris tumor was diagnosed as prostate cancer metastasis and the literature was searched using medline ...
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