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new advances in mass spectrometry-based proteomics technology are having amajor impact on our understanding of how human spermatozoa acquire their capacity for fertilization. a complete analysis of the proteins found in the human spermatozoa is essential for understanding the events leading up to, and including, fertilization and early embryo development. in this short review, we have collected...

morphine’s effects on learning and memory processes are well known to depend on synaptic plasticity in the hippocampus. whereas the role of the hippocampus in morphine-induced amnesia and state-dependent learning is established, the biochemical and molecular mechanisms underlying these processes are poorly understood. the present study intended to investigate whether administration of morphine ...

background: dihydropyrimidinase related proteins (drps) have known homologous to the collapsing response mediator proteins (crmps). the drp gene family has comprised four members, drp 1, 2, 3, and 4, all out of which have considered to be involved in axonal outgrowth and path-finding. methods: the protein has extracted from tumor, normal brain tissues, and then the protein purity has evaluated ...

Two-dimensional electrophoresis has nurtured the birth of proteomics. It is however no longer the exclusive setup used in proteomics, with the development of shotgun proteomics techniques that appear more fancy and fashionable nowadays.Nevertheless, 2D gel-based proteomics still has valuable features, and sometimes unique ones, which make it often an attractive choice when a proteomics strategy...

This review is intended to give readers a snapshot of current mass spectrometry for proteomics research. It covers a brief history of mass spectrometry proteomic research, peptidomics and proteomics for biomarker search, quantitative proteomics, proteomics with post-translational modification and future perspective of proteomics.

Proteomics is a branch of molecular biology that deals with the identification and quantification proteins in living objects, as well analysis protein functions their interactions.
 studied by are expressed given cell, tissue or organism over period time (under certain conditions).
 It known information about primary structure (the sequence amino acid residues protein) contained struc...

Bioinformatics is a fast evolving field that combines biology, computer science, and statistics to analyze comprehend enormous volumes of biological data. As result the introduction high-throughput technologies like next-generation sequencing mass spectrometry, genomic proteomics research has generated data, necessitating development computational tools process extract useful insights from thes...

Proteomics, the large-scale study of all proteins an organism or system, is a powerful tool for studying biological systems. It can provide holistic view physiological and biochemical states given samples through identification quantification large numbers peptides proteins. In forensic science, proteomics be used as confirmatory orthogonal technique well-built genomic analyses. Proteomics high...