Once the safety issue has been overcome, induced pluripotent stem cells (iPSCs), which do not entail ethical or immunological concerns, may become the preferred cell source for regenerative medicine. Various types of iPSCs have been established by different methods, and each type exhibits different biological properties. Before iPSC-based clinical applications can be initiated, detailed evaluat...

In vivo, homozygous staggerer (Rora(sg/sg)) Purkinje cells (PCs) remain in an early stage of development with rudimentary spineless dendrites, associated with a lack of parallel fiber (PF) input and the persistence of multiple climbing fibers (CFs). In this immunocytochemical study we used cerebellar organotypic cultures to monitor the development of Rora(sg/sg) PF-PC synapses in the absence of...

PURPOSE Evaluate the different types of conduction blocks obtained between inferior vena cava-tricuspid annulus (posterior isthmus) and between tricuspid annulus-coronary sinus ostium (septal isthmus) after radiofrequency (RF) catheter ablation of atrial flutter (AFL). METHODS In 16 procedures, 14 patients (pts), 9 male, with type I AFL underwent RF ablation. Atrial activation around tricuspi...

In this study, we examined the effects of elastic wrist taping with different pressure levels on the maximum grip strength. The subjects were 20 healthy male university students. The tape was wrapped three times around the wrist at the radial and ulnar styloid process. Taping pressure was measured using a pressure measuring system for stockings and bandages. A pressure sensor was placed over th...

Background: Double-J (DJ) stent is an integral part of urologic practice. DJ stents can have numerous complications such as persistent irritative symptoms, encrustations, and up and down migrations within the pelvicaliceal system (PCS), but displacement outside the urinary tract is rare. We are presenting a unique case of DJ stent lying outside the PCS for more than a decade. Case Presentation:...

Myosin Va is an actin-based molecular motor that is involved in organelle transport and membrane trafficking. Here, we explored the role of myosin Va in the formation of synaptic circuitry by examining climbing fiber (CF) innervation of Purkinje cells (PCs) in the cerebella of dilute-neurological (d-n) mice and dilute-opisthotonus (dop) rats that have mutations in dilute-encoded myosin Va. Ante...

We read with great interest a meta-analysis by Jaffery et al. [1] of randomized control trials (RCTs) comparing minimally invasive direct coronary artery bypass (MIDCAB) versus percutaneous coronary stenting (PCS) for stenosis of the proximal left anterior descending artery (LAD). Between PCS and MIDCAB, there was no difference in major adverse cardiac events (MACE), i.e. the composite end poin...

The typically positive relationship between cognitive reappraisal and psychological functioning may be nullified for Latinos embedded within multiple contexts of oppression (Perez & Soto, 2011). Multiply oppressive contexts are characterized by exposure to oppression at a societal level (distal oppression), in the immediate environment (proximal oppression), and at an individual level (personal...