OBJECTIVES To assess the prevalence, levels of antimicrobial susceptibility and resistance mechanisms of Pseudomonas. METHODS A total of 445 clinical isolates and 200 environmental isolates were collected from three hospitals in Minia, Egypt. The MICs of different antibiotics were determined using the agar dilution method. The isolates were tested for beta-lactamase production and for the pre...

Prompt detection of metallo-beta-lactamase (MBL) producing isolates is necessary to prevent their dissemination. Frequency of MBLs producing strains among multidrug resistant (MDR) Acinetobacter species and Pseudomonas aeruginosa was evaluated in critical care patients using imipenem-EDTA disk method. One hundred MDR Acinetobacter spp. and 42 Pseudomonas aeruginosa were checked for MBL producti...

The results of this study suggest that the transduction of antibiotic resistance genes by wild-type phages is an additional mechanism of spread amongst strains of P. aeruginosa. The emergence of lysogenic, multidrug-resistant strains, therefore, should be closely monitored. tobramycin resistance in Pseudomonas aeruginosa with phage F 116 and AP 19, a new wild-type phage. Zentralblatt für Bakter...

Pseudomonas aeruginosa exotoxin A (PA), a potent protein synthesis inhibitor, was found to be a weak T-cell mitogen for murine splenocytes. Maximal stimulation of [3H]thymidine incorporation was obtained with 10 to 100 ng of toxin per ml following a 4-day induction. PA was also shown to be a polyclonal activator of cytolytic T lymphocytes (CTL), effective against concanavalin A-treated target c...

[This corrects the article on p. 532 in vol. 7, PMID: 29379773.].

UNLABELLED The aim of our study was to determine the prevalence of Pseudomonas aeruginosa bacteremia, risk factors, and outcome of patients treated at the Hospital of Kaunas University of Medicine. MATERIAL AND METHODS All hospitalized patients with blood culture positive for Pseudomonas aeruginosa during the 5-year period were included. A retrospective data analysis was performed to evaluate...

Contamination of fluorescein solutions by Pseudomonas aeruginosa has been a concern of ophthalmologists for many years because of the severity of pseudomonas keratitis. Attempts to prevent contamination have been directed at stringent sterility control during manufacture and the introduction of single-dose disposable containers such as Minims. Deliberate contamination of Minims fluorescein with...

b a ckground: quorum-sensing systems regulate expression of several virulence factors in pseudomonas aeruginosa . this study investigated the relation between expression of the las quorum-sensing system and expression of mexy and ampc in35 clinical isolates of p. aeruginosa . m e t hods: antibiotic susceptibility was determined by the disc diffusion method according to the clinical and laborato...