CONTEXT Although Pseudomonas aeruginosa is the most common virulent respiratory pathogen in cystic fibrosis (CF), the longitudinal development of P aeruginosa infection and its effect on antibody responses and lung disease progression in children with CF remain unclear. OBJECTIVE To prospectively examine the epidemiology of P aeruginosa infection and its impact on CF pulmonary morbidity. DE...

Due to the greater in vitro activity of ciprofloxacin than that of levofloxacin against Pseudomonas aeruginosa, the likelihood of isolating a clinical strain of quinolone-resistant (QR) P. aeruginosa might be greater after exposure to levofloxacin than ciprofloxacin. We examined the risk of isolating QR P. aeruginosa in association with prior levofloxacin or ciprofloxacin exposure. A case-case-...

[1] Site preference (SP), the difference in dN between the central and outer nitrogen atoms in N2O, is a powerful approach for apportioning fluxes of N2O from soils to nitrification and denitrification (Sutka et al., 2006). A critical aspect of the use of SP data to apportion sources of N2O to nitrification and denitrification is the need to evaluate data for isotope shifts that may have occurr...

metallo β-lactamases (mbls) producing pseudomonas aeruginosa ( p. aeruginosa ) isolates are becoming an escalating global threat. among the antibiotics used to treat infections associated with p. aeruginosa , resistance to carbapenem is a serious therapeutic challenge. the aim of the present study was to detect mbl-producing p. aeruginosa and to evaluate the extracts of urtica. dioica , carum. ...

Non-cystic fibrosis bronchiectasis (NCFBE) is a rare, chronic lung disease characterized by bronchial inflammation and permanent airway dilation. Chronic infections with P. aeruginosa have been linked to higher morbidity and mortality. To understand the impact of P. aeruginosa in NCFBE on health care costs and burden, we assessed healthcare costs and utilization before and after P. aeruginosa d...

nosocomial infections of multidrug-resistant pseudomonas aeruginosa (mdrpa) are a growing concern in hospitalized patients in burn centers. the aim of this study was to investigate the flagellin profiling and antibiotic susceptibility of p. aeruginosa isolated from burn wound infections. during 8 month study, 73 clinically p. aeruginosa isolates collected from patients hospitalized in burn ward...

To explore the mechanism of immunosuppression associated with sepsis, we developed a murine model of sepsis-induced Pseudomonas aeruginosa pneumonia. CD-1 mice underwent either cecal ligation and 26-gauge needle puncture (CLP) or sham surgery, followed by the intratracheal (i.t.) administration of P. aeruginosa or saline. Survival in mice undergoing CLP followed 24 h later by the i.t. administr...